{{Rsnum
|rsid=6125048
|Gene=NCOA3
|Chromosome=20
|position=47579861
|Orientation=plus
|GMAF=0.152
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(G;G)
|geno2=(G;T)
|geno3=(T;T)
|Gene_s=NCOA3
}}{{ population diversity
| geno1=(G;G)
| geno2=(G;T)
| geno3=(T;T)
| CEU | 100.0 | 0.0 | 0.0
| HCB | 26.3 | 54.7 | 19.0
| JPT | 31.9 | 48.7 | 19.5
| YRI | 96.6 | 3.4 | 0.0
| ASW | 96.5 | 3.5 | 0.0
| CHB | 26.3 | 54.7 | 19.0
| CHD | 37.6 | 47.7 | 14.7
| GIH | 83.0 | 16.0 | 1.0
| LWK | 98.2 | 1.8 | 0.0
| MEX | 54.4 | 38.6 | 7.0
| MKK | 89.7 | 10.3 | 0.0
| TSI | 0.0 | 0.0 | 0.0
| HapMapRevision=28
}}
{{PMID Auto GWAS
|PMID=19176441
|Trait=Treatment response for acute lymphoblastic leukemia
|Title=Genome-wide interrogation of germline genetic variation associated with treatment response in childhood acute lymphoblastic leukemia
|RiskAllele=T
|Pval=0.000002
|OR=2.73
|ORtxt=[1.08-6.88]
|OA=1
}}

{{PharmGKB
|RSID=rs6125048
|Name_s=
|Gene_s=NCOA3
|Feature=
|Evidence=PubMed ID:19176441; Web Resource:http://www.genome.gov/gwastudies/
|Annotation=GWAS results: Genome-wide interrogation of germline genetic variation associated with treatment response in childhood acute lymphoblastic leukemia. (Initial Sample Size: 487 children; Replication Sample Size: NR); (Region: 20q13.12; Reported Gene(s): NCOA3; Risk Allele: rs6125048-T); (p-value= 0.000002).This variant is associated with Treatment response for acute lymphoblastic leukemia.
|Drugs=
|Drug Classes=
|Diseases=Precursor Cell Lymphoblastic Leukemia-Lymphoma
|Curation Level=Non-Curated
|PharmGKB Accession ID=PA164740035
}}

{{PharmGKB
|RSID=rs6125048
|Name_s=
|Gene_s=NCOA3
|Feature=
|Evidence=PubMed ID:19176441
|Annotation=This variant is associated with end-of-induction minimal risidual disease (MRD) in childhood acute lymphoblastic leukemia (ALL) from 2 independent cohorts (GWAS result). Risk Allele: T, MAF= 0.04, combined P value= 2.34E-06.
|Drugs=
|Drug Classes=
|Diseases=Neoplasm, Residual; Precursor Cell Lymphoblastic Leukemia-Lymphoma
|Curation Level=Curated
|PharmGKB Accession ID=PA162470153
}}

{{GET Evidence
|impact=pathogenic
|qualified_impact=Insufficiently evaluated pathogenic
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs6125048
|overall_frequency_n=13
|overall_frequency_d=128
|overall_frequency=0.101562
|n_genomes=10
|n_genomes_annotated=0
|n_haplomes=11
|n_articles=1
|n_articles_annotated=0
|in_gwas=Y
|in_pharmgkb=Y
|autoscore=2
|webscore=N
}}

{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | Affy GenomeWide 6}}
{{on chip | HumanOmni1Quad}}