{{Rsnum
|rsid=6136
|Gene=SELP
|Chromosome=1
|position=169594713
|Orientation=plus
|ReferenceAllele=A
|MissenseAllele=C
|GMAF=0.04408
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(A;A)
|geno2=(A;C)
|geno3=(C;C)
|Gene_s=SELP
}}{{ population diversity
| geno1=(A;A)
| geno2=(A;C)
| geno3=(C;C)
| CEU | 80.0 | 20.0 | 0.0
| HCB | 97.8 | 2.2 | 0.0
| JPT | 100.0 | 0.0 | 0.0
| YRI | 100.0 | 0.0 | 0.0
| ASW | 94.5 | 1.8 | 3.6
| CHB | 97.8 | 2.2 | 0.0
| CHD | 0.0 | 0.0 | 0.0
| GIH | 94.8 | 2.1 | 3.1
| LWK | 0.0 | 0.0 | 0.0
| MEX | 0.0 | 0.0 | 0.0
| MKK | 0.0 | 0.0 | 0.0
| TSI | 0.0 | 0.0 | 0.0
| HapMapRevision=28
}}{{PMID|17944986}}  cardiovascular risk

{{PMID Auto GWAS
|PMID=20167578
|Trait=Soluble levels of adhesion molecules
|Title=Large-scale genomic studies reveal central role of ABO in sP-selectin and sICAM-1 levels
|RiskAllele=T
|Pval=4E-61
|OR=22.60
|ORtxt=[19.86-25.34] % increase
|OA=1
}}

{{omim
|id=173610
|rsnum=6136
|variant=0001
}}

{{PMID Auto
|PMID=22473907
|Title=P-selectin genotype is associated with the development of cancer cachexia
|OA=1
}}

{{ClinVar
|rsid=6136
|Reversed=1
|FwdREF=A
|FwdALT=C
|REF=T
|ALT=G
|RSPOS=169594713
|CHROM=1
|GMAF=0.044
|dbSNPBuildID=52
|SSR=0
|SAO=1
|VP=0x050178000a15150517130110
|GENEINFO=SELP:6403
|GENE_NAME=SELP
|GENE_ID=6403
|WGT=1
|VC=SNV
|CLNALLE=1
|CLNHGVS=NC_000001.11:g.169594713T>G
|CLNORIGIN=1
|CLNSIG=2
|Tags=RV;PM;TPA;PMC;SLO;NSM;REF;OTH;ASP;VLD;G5;HD;GNO;KGPhase1;KGPROD;OTHERKG;PH3;LSD;MTP;OM;NOC
|CAF=0.9559; 0.04408
|CLNACC=RCV000014482.1
|CLNDBN=SELECTIN P POLYMORPHISM
|CLNSRC=ClinVar; OMIM Allelic Variant
|CLNSRCID=NM_003005.3:c.2266A>C; 173610.0001
|COMMON=1
|Disease=SELECTIN P POLYMORPHISM
}}

{{PMID Auto
|PMID=16820586
|Title=Inflammatory gene polymorphisms and risk of postoperative myocardial infarction after cardiac surgery.
|OA=1
}}

{{PMID Auto
|PMID=19404301
|Title=Variation in the upstream region of P-Selectin (SELP) is a risk factor for SLE.
|OA=1
}}

{{GET Evidence
|gene=SELP
|aa_change=Thr756Pro
|aa_change_short=T756P
|impact=not reviewed
|qualified_impact=Insufficiently evaluated not reviewed
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs6136
|overall_frequency_n=816
|overall_frequency_d=10758
|overall_frequency=0.0758505
|n_genomes=3
|n_genomes_annotated=0
|n_haplomes=3
|n_articles=0
|n_articles_annotated=0
|nblosum100=4
|autoscore=1
|n_web_uneval=9
}}

{{PMID Auto
|PMID=24504449
|Title=SELP genetic polymorphisms may contribute to the pathogenesis of coronary heart disease and myocardial infarction: a meta-analysis
}}

{{PMID Auto
|PMID=25147926
|Title=Cellular Adhesion Gene SELP Is Associated with Rheumatoid Arthritis and Displays Differential Allelic Expression
}}
{{on chip | 23andMe v1}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | FTDNA2}}
{{on chip | FTDNA}}
{{on chip | HumanOmni1Quad}}
{{on chip | Illumina Human 1M}}