{{Rsnum
|rsid=61816761
|Gene=FLG
|Chromosome=1
|position=152313385
|Orientation=plus
|GMAF=0.00551
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(A;A)
|geno2=(A;G)
|geno3=(G;G)
|Gene_s=FLG,FLG-AS1
}}{{omim
|id=135940
|rsnum=61816761
|variant=0001
}}{{ClinVar
|rsid=61816761
|Reversed=0
|FwdREF=G
|FwdALT=A
|REF=G
|ALT=A
|RSPOS=152313385
|CHROM=1
|GMAF=0.0055
|dbSNPBuildID=129
|SSR=0
|SAO=1
|VP=0x050060020605040116110100
|GENEINFO=FLG:2312; FLG-AS1:339400
|GENE_NAME=FLG; FLG-AS1
|GENE_ID=2312; 339400
|WGT=1
|VC=SNV
|CLNALLE=1
|CLNHGVS=NC_000001.11:g.152313385G>A
|CLNSRC=ClinVar; GTR; OMIM Allelic Variant
|CLNORIGIN=1
|CLNSRCID=NM_002016.1:c.1501C>T; NR_103778.1:n.-74G>A; GTR000328553; 135940.0001
|CLNSIG=255
|CLNCUI=C0079584
|CLNDBN=Ichthyosis vulgaris; Dermatitis, atopic, 2, susceptibility to
|Disease=Ichthyosis vulgaris; Dermatitis
|CLNACC=RCV000017712.26; RCV000017713.1
|Tags=PM;NSN;REF;R5;ASP;VLD;GNO;KGPhase1;KGPROD;OTHERKG;LSD;OM
|CAF=0.9945; 0.00551
|CLNDSDB=MedGen:OMIM
|CLNDSDBID=C0079584:146700
|COMMON=1
}}
{{PMID Auto
|PMID=22069270
|OA=1
}} rs61816761 is located in the FLG locus; one of the major loci associated with atopic dermatitis and asthma predisposition. In this study of 7688 type 1 diabetes patients and 9354 controls, the association between rs61816761 and type 1 diabetes was examined. The odds ratios (95% confidence intervals) were 1.01 (0.88-1.17), 1.02 (0.88-1.18), and 0.88 (0.20-3.81) for the T, T;C, and T;T minor alleles/genotypes, respectively, as compared to C;C (P=0.082). In other words, there is no association between Rs61816761 and type 1 diabetes.