{{Rsnum
|rsid=62256378
|geno1=(A;A)
|geno2=(A;G)
|geno3=(G;G)
|Chromosome=3
|Orientation=plus
|Gene=SUCLG2
|position=67406609
|Gene_s=SUCLG2
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
}}It was found that the minor allele (A) of rs62256378 in the SUCLG2 gene significantly reduced cognitive decline in AD patients (p=3.1x10-3,beta=0.32) {Beta represents attenuation in cognitive decline as measured in standard deviations of MMSE). This was only significant in epsilon 4 non carriers (p=0.021).

Hum Mol Genet. 2014 Jul 15. pii: ddu372. 
SUCLG2 identified as both a determinator of CSF Aβ1-42-levels and an attenuator of cognitive decline in Alzheimer's disease
{{PMID|25027320}}