{{Rsnum
|rsid=63750875
|Chromosome=2
|Orientation=plus
|geno1=(C;C)
|geno2=(C;G)
|geno3=(G;G)
|Gene=MSH2
|position=47475171
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|Gene_s=MSH2
}}{{omim
|id=609309
|rsnum=63750875
|variant=0012
}}

{{ClinVar
|rsid=63750875
|Reversed=0
|FwdREF=G
|FwdALT=C
|REF=G
|ALT=C
|RSPOS=47702310
|CHROM=2
|dbSNPBuildID=132
|SSR=0
|SAO=1
|VP=0x050268000000000002110100
|GENEINFO=MSH2:4436
|GENE_NAME=MSH2
|GENE_ID=4436
|WGT=0
|VC=SNV
|CLNALLE=1
|CLNHGVS=NC_000002.11:g.47702310G>C
|CLNSRC=InSiGHT; OMIM Allelic Variant
|CLNORIGIN=1
|CLNSRCID=c.1906G>C; 609309.0012
|CLNSIG=5
|CLNCUI=CN068508
|CLNDBN=Colorectal cancer, hereditary, nonpolyposis, type 1; Lynch syndrome
|Disease=Colorectal cancer; Lynch syndrome
|CLNACC=RCV000001834.1; RCV000030245.2
|Tags=PM;PMC;S3D;OTHERKG;LSD;OM
|CLNDSDB=MedGen; GeneReviews:MedGen:SNOMED_CT
|CLNDSDBID=CN068508; NBK1211:C0009405:315058005
}}

{{PMID|15516}} Characterization of chicken liver dihydrofolate reductase after purification by affinity chromatography and isoelectric focusing.

{{PMID|17414604|OA=1
}} Single-amplicon MSH2 A636P mutation testing in Ashkenazi Jewish patients with colorectal cancer: role in presurgical management.

{{PMID|19101824}} Homozygosity of MSH2 c.1906G-->C germline mutation is associated with childhood colon cancer, astrocytoma and signs of Neurofibromatosis type I.

{{PMID|19267393|OA=1
}} Classifying MLH1 and MSH2 variants using bioinformatic prediction, splicing assays, segregation, and tumor characteristics.

{{PMID|20850175}} The rate of the predominant Jewish mutations in the BRCA1, BRCA2, MSH2 and MSH6 genes in unselected Jewish endometrial cancer patients.

{{PMID|21419771}} High risk of colorectal and endometrial cancer in Ashkenazi families with the MSH2 A636P founder mutation.

{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}