{{Rsnum
|rsid=642742
|Chromosome=12
|position=88905969
|Orientation=minus
|GMAF=0.3714
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|Summary=skin color
|geno1=(A;A)
|geno2=(A;G)
|geno3=(G;G)
}}{{ population diversity
| geno1=(A;A)
| geno2=(A;G)
| geno3=(G;G)
| CEU | 0.9 | 32.7 | 66.4
| HCB | 10.9 | 38.0 | 51.1
| JPT | 1.8 | 25.7 | 72.6
| YRI | 88.9 | 11.1 | 0.0
| ASW | 57.9 | 36.8 | 5.3
| CHB | 10.9 | 38.0 | 51.1
| CHD | 1.8 | 34.9 | 63.3
| GIH | 5.0 | 29.7 | 65.3
| LWK | 82.6 | 17.4 | 0.0
| MEX | 5.2 | 46.6 | 48.3
| MKK | 55.8 | 35.9 | 8.3
| TSI | 7.8 | 33.3 | 58.8
| HapMapRevision=28
}}Influences [[appearance]] [http://scienceblogs.com/gnxp/2009/03/genetics_of_human_pigmentation.php?utm_source=sbhomepage&utm_medium=link&utm_content=channellink gnxp]
For the rs642742 SNP (184745.0002), located 326 kb upstream of the KITLG transcription start site, the frequency of the ancestral A allele is at least 92% in West Africans, whereas the frequency of the derived G allele is at least 86% in Europeans and East Asians. Admixture mapping suggested that replacement of AA with GG in the rs642742 SNP may account for a lightening of a person's skin by 6 to 7 melanin units. In comparison, the overall skin reflectance difference between West Africans and Europeans is 30 melanin units.

{{omim
|desc=SKIN/HAIR/EYE PIGMENTATION, VARIATION IN, 7; SHEP7
|id=611664
|rsnum=642742
}}

{{omim
|id=184745
|desc=KIT LIGAND; KITLG
|rsnum=642742
}}

{{omim
|id=184745
|rsnum=642742
|variant=0002
}}

{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | FTDNA2}}
{{on chip | HumanOmni1Quad}}
{{on chip | Illumina Human 1M}}