{{Rsnum
|rsid=6457327
|Chromosome=6
|position=31106253
|Orientation=plus
|GMAF=0.3347
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(A;A)
|geno2=(A;C)
|geno3=(C;C)
}}{{ population diversity
| geno1=(A;A)
| geno2=(A;C)
| geno3=(C;C)
| CEU | 16.8 | 47.8 | 35.4
| HCB | 11.7 | 33.6 | 54.7
| JPT | 13.3 | 49.6 | 37.2
| YRI | 10.9 | 37.4 | 51.7
| ASW | 5.3 | 42.1 | 52.6
| CHB | 11.7 | 33.6 | 54.7
| CHD | 13.8 | 49.5 | 36.7
| GIH | 3.0 | 27.7 | 69.3
| LWK | 4.5 | 26.4 | 69.1
| MEX | 13.8 | 46.6 | 39.7
| MKK | 3.2 | 29.5 | 67.3
| TSI | 7.8 | 45.1 | 47.1
| HapMapRevision=28
}}
[http://www.eurekalert.org/pub_releases/2009-07/ttgr-glt071509.php news] the presence of the G allele was protective against follicular lymphoma, while the presence of the A allele was predictive of an increased risk of developing follicular lymphoma. Dr. Brown said individuals who had the A variant were nearly twice as likely to develop follicular lymphoma.

[http://blog.23andme.com/2009/07/23/snpwatch-genetic-variant-may-increase-risk-of-follicular-lymphoma/ 23andMe blog] coverage

{{PMID Auto GWAS
|PMID=19620980
|Trait=Follicular lymphoma
|Title=Genetics variants at 6p21.33 are associated with susceptibility to follicular lymphoma
|RiskAllele=C
|Pval=5E-11
|OR=1.69
|ORtxt=[1.43-2.00]
|OA=1
}}

{{PMID Auto GWAS
|PMID=20639881
|Trait=Follicular lymphoma
|Title=Genome-wide association study of follicular lymphoma identifies a risk locus at 6p21.32
|RiskAllele=C
|Pval=0.000007
|OR=1.47
|ORtxt=[1.27-1.72]
|OA=1
}}
{{PMID Auto
|PMID=21233317
|Title=SNP rs6457327 in the HLA region on chromosome 6p is predictive of the transformation of follicular lymphoma
|OA=1
}}

{{omim
|id=613024
|rsnum=6457327
}}

{{GET Evidence
|impact=pathogenic
|qualified_impact=Insufficiently evaluated pathogenic
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs6457327
|overall_frequency_n=85
|overall_frequency_d=128
|overall_frequency=0.664062
|n_genomes=47
|n_genomes_annotated=0
|n_haplomes=71
|n_articles=0
|n_articles_annotated=0
|in_gwas=Y
|autoscore=2
|webscore=N
}}

{{on chip | 23andMe v1}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | HumanOmni1Quad}}
{{on chip | Illumina Human 1M}}