{{Rsnum
|rsid=6463462
|Gene=UPP1
|Chromosome=7
|position=48102597
|Orientation=plus
|GMAF=0.4192
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(G;G)
|geno2=(G;T)
|geno3=(T;T)
|Gene_s=UPP1
}}{{ population diversity
| geno1=(G;G)
| geno2=(G;T)
| geno3=(T;T)
| CEU | 17.7 | 43.4 | 38.9
| HCB | 14.7 | 49.3 | 36.0
| JPT | 20.4 | 52.2 | 27.4
| YRI | 15.0 | 41.5 | 43.5
| ASW | 12.3 | 66.7 | 21.1
| CHB | 14.7 | 49.3 | 36.0
| CHD | 19.3 | 48.6 | 32.1
| GIH | 5.9 | 41.6 | 52.5
| LWK | 14.5 | 53.6 | 31.8
| MEX | 24.1 | 41.4 | 34.5
| MKK | 18.6 | 59.0 | 22.4
| TSI | 12.7 | 55.9 | 31.4
| HapMapRevision=28
}}{{PharmGKB
|RSID=rs6463462
|Name_s=
|Gene_s=UPP1
|Feature=
|Evidence=PubMed ID:19268276
|Annotation=In a GWAS of 3497 Dutch subjects from the Netherlands Study of Depression and Anxiety or from the Netherlands Twin Registry, this SNP was found to be associated with Current Smoking (p = 0.00007957;OR for minor allele G:0.81).
|Drugs=nicotine
|Drug Classes=
|Diseases=
|Curation Level=Curated
|PharmGKB Accession ID=PA164924511
}}

{{GET Evidence
|impact=pharmacogenetic
|qualified_impact=Insufficiently evaluated pharmacogenetic
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs6463462
|overall_frequency_n=85
|overall_frequency_d=128
|overall_frequency=0.664062
|n_genomes=50
|n_genomes_annotated=0
|n_haplomes=74
|n_articles=1
|n_articles_annotated=0
|in_pharmgkb=Y
|autoscore=1
|webscore=N
}}

{{on chip | 23andMe v1}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | FTDNA2}}
{{on chip | FTDNA}}
{{on chip | HumanOmni1Quad}}
{{on chip | Illumina Human 1M}}