{{Rsnum
|rsid=6469804
|Chromosome=8
|position=119032590
|Orientation=plus
|GMAF=0.2773
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(A;A)
|geno2=(A;G)
|geno3=(G;G)
|Gene=COLEC10
|Gene_s=COLEC10
}}{{ population diversity
| geno1=(A;A)
| geno2=(A;G)
| geno3=(G;G)
| CEU | 28.3 | 54.0 | 17.7
| HCB | 51.8 | 44.5 | 3.6
| JPT | 55.4 | 36.6 | 8.0
| YRI | 100.0 | 0.0 | 0.0
| ASW | 75.4 | 22.8 | 1.8
| CHB | 51.8 | 44.5 | 3.6
| CHD | 65.7 | 30.6 | 3.7
| GIH | 55.4 | 38.6 | 5.9
| LWK | 96.4 | 3.6 | 0.0
| MEX | 32.8 | 44.8 | 22.4
| MKK | 78.8 | 20.5 | 0.6
| TSI | 44.1 | 40.2 | 15.7
| HapMapRevision=28
}}

[http://www.medpagetoday.com/Endocrinology/Osteoporosis/tb/9271 news] [[rs6469792]] and [[rs6469804]] association with bone mineral density.

{{GWAS Summary
|SNP=rs6469804
|PubMedID=18445777
|Condition=Bone mineral density (spine)
|Gene=OPG
|Risk Allele=A
|pValue=7.00E-015
|OR=0.12
|95CI=0.09-0.15) SD decreas
}}

{{omim
|desc=BONE MINERAL DENSITY QUANTITATIVE TRAIT LOCUS 10; BMND10
|id=612113
|rsnum=6469804
}}

{{PharmGKB
|RSID=rs6469804
|Name_s=
|Gene_s=-
|Feature=
|Evidence=PubMed ID:18445777; Web Resource:http://www.genome.gov/gwastudies/
|Annotation=GWAS Results: Multiple Genetic Loci for Bone Mineral Density and Fractures (Initial Sample Size: 5,861 individuals; Replication Sample Size: 7,925 individuals; Risk Allele: rs6469804-A). This variant is associated with Bone mineral density (spine).
|Drugs=
|Drug Classes=
|Diseases=Bone Diseases; Bone Diseases, Metabolic; Fractures, Bone
|Curation Level=Non-Curated
|PharmGKB Accession ID=PA162356558
}}

{{PMID Auto
|PMID=18455228
|Title=Bone mineral density, osteoporosis, and osteoporotic fractures: a genome-wide association study.
|OA=1
}}

{{PMID Auto
|PMID=19181680
|Title=Common variants in the region around Osterix are associated with bone mineral density and growth in childhood.
|OA=1
}}

{{PMID Auto
|PMID=20548944
|Title=An integration of genome-wide association study and gene expression profiling to prioritize the discovery of novel susceptibility Loci for osteoporosis-related traits.
|OA=1
}}

{{PMID Auto
|PMID=20554715
|Title=Analysis of recently identified osteoporosis susceptibility genes in Han Chinese women.
}}

{{GET Evidence
|impact=pathogenic
|qualified_impact=Insufficiently evaluated pathogenic
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs6469804
|overall_frequency_n=88
|overall_frequency_d=128
|overall_frequency=0.6875
|n_genomes=46
|n_genomes_annotated=0
|n_haplomes=80
|n_articles=0
|n_articles_annotated=0
|in_gwas=Y
|in_pharmgkb=Y
|autoscore=2
|webscore=N
}}

{{on chip | 23andMe v1}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | HumanOmni1Quad}}
{{on chip | Illumina Human 1M}}