{{Rsnum
|rsid=6495122
|Gene=CPLX3
|Chromosome=15
|position=74833304
|Orientation=plus
|GMAF=0.3522
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(A;A)
|geno2=(A;C)
|geno3=(C;C)
}}{{ population diversity
| geno1=(A;A)
| geno2=(A;C)
| geno3=(C;C)
| CEU | 17.9 | 40.2 | 42.0
| HCB | 62.5 | 33.8 | 3.7
| JPT | 61.1 | 32.7 | 6.2
| YRI | 59.9 | 36.1 | 4.1
| ASW | 50.9 | 43.9 | 5.3
| CHB | 62.5 | 33.8 | 3.7
| CHD | 77.1 | 22.9 | 0.0
| GIH | 83.2 | 16.8 | 0.0
| LWK | 75.5 | 21.8 | 2.7
| MEX | 27.6 | 53.4 | 19.0
| MKK | 55.8 | 32.1 | 12.2
| TSI | 28.4 | 55.9 | 15.7
| HapMapRevision=28
}}[http://blog.23andme.com/2009/05/12/snpwatch-researchers-find-more-genetic-variations-associated-with-blood-pressure/ 23andMe blog] [[blood pressure]]

{{PMID Auto GWAS
|PMID=19430479
|Trait=Diastolic Blood Pressure
|Title=Genome-wide association study of blood pressure and hypertension
|RiskAllele=A
|Pval=2E-10
|OR=0.40
|ORtxt=[0.28-0.52] mm Hg increase
|OA=1
}}

{{PMID Auto GWAS
|PMID=21490707
|Trait=None
|Title=Genome-wide meta-analysis identifies regions on 7p21 (AHR) and 15q24 (CYP1A2) as determinants of habitual caffeine consumption.
|RiskAllele=A
|Pval=6E-7
|OR=0.0700
|ORtxt=[0.05-0.09]  mg/day decrease
|OA=1
}}

{{PMID Auto GWAS
|PMID=21876539
|Trait=None
|Title=Genome-wide association analysis of coffee drinking suggests association with CYP1A1/CYP1A2 and NRCAM.
|RiskAllele=A
|Pval=7E-9
|OR=0.0500
|ORtxt=[0.03-0.07] unit decrease
|OA=1
}}

{{GET Evidence
|impact=pathogenic
|qualified_impact=Insufficiently evaluated pathogenic
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs6495122
|overall_frequency_n=34
|overall_frequency_d=118
|overall_frequency=0.288136
|n_genomes=23
|n_genomes_annotated=0
|n_haplomes=27
|n_articles=0
|n_articles_annotated=0
|in_gwas=Y
|autoscore=1
|webscore=N
}}

{{on chip | 23andMe v1}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | HumanOmni1Quad}}
{{on chip | Illumina Human 1M}}