{{Rsnum
|rsid=6495308
|Gene=CHRNA3
|Chromosome=15
|position=78615314
|Orientation=plus
|GMAF=0.4389
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(C;C)
|geno2=(C;T)
|geno3=(T;T)
|Gene_s=CHRNA3
}}{{ population diversity
| geno1=(C;C)
| geno2=(C;T)
| geno3=(T;T)
| CEU | 4.5 | 33.0 | 62.5
| HCB | 47.4 | 45.3 | 7.3
| JPT | 61.9 | 33.6 | 4.4
| YRI | 12.9 | 46.3 | 40.8
| ASW | 17.5 | 33.3 | 49.1
| CHB | 47.4 | 45.3 | 7.3
| CHD | 51.4 | 40.4 | 8.3
| GIH | 24.8 | 46.5 | 28.7
| LWK | 17.3 | 53.6 | 29.1
| MEX | 32.8 | 44.8 | 22.4
| MKK | 5.8 | 42.9 | 51.3
| TSI | 5.9 | 35.3 | 58.8
| HapMapRevision=28
}}{{PMID Auto
|PMID=20418889
|Title=Meta-analysis and imputation refines the association of 15q25 with smoking quantity
|OA=1
}}

{{PMID Auto
|PMID=18165968
|Title=Identification of pharmacogenetic markers in smoking cessation therapy.
|OA=1
}}

{{PMID Auto
|PMID=18227835
|Title=Alpha-5/alpha-3 nicotinic receptor subunit alleles increase risk for heavy smoking.
|OA=1
}}

{{PMID Auto
|PMID=18519524
|Title=Variants in nicotinic receptors and risk for nicotine dependence.
|OA=1
}}

{{PMID Auto
|PMID=18571741
|Title=Genetic variability in nicotinic acetylcholine receptors and nicotine addiction: converging evidence from human and animal research.
|OA=1
}}

{{PMID Auto
|PMID=19259974
|Title=Multiple distinct risk loci for nicotine dependence identified by dense coverage of the complete family of nicotinic receptor subunit (CHRN) genes.
|OA=1
}}

{{PMID Auto
|PMID=19443489
|Title=Risk for nicotine dependence and lung cancer is conferred by mRNA expression levels and amino acid change in CHRNA5.
|OA=1
}}

{{PMID Auto
|PMID=19706762
|Title=The CHRNA5-CHRNA3-CHRNB4 nicotinic receptor subunit gene cluster affects risk for nicotine dependence in African-Americans and in European-Americans.
|OA=1
}}

{{PMID Auto
|PMID=20700436
|Title=Multiple independent loci at chromosome 15q25.1 affect smoking quantity: a meta-analysis and comparison with lung cancer and COPD.
|OA=1
}}

{{PMID Auto
|PMID=20808433
|Title=Associations of variants in CHRNA5/A3/B4 gene cluster with smoking behaviors in a Korean population.
|OA=1
}}

{{PMID Auto
|PMID=22223462
|Title=Alpha-5 and -3 nicotinic receptor gene variants predict nicotine dependence but not cessation: findings from the COMMIT cohort.
|OA=1
}}

{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | Affy GenomeWide 6}}
{{on chip | FTDNA2}}
{{on chip | FTDNA}}
{{on chip | HumanOmni1Quad}}
{{on chip | NatGeo2}}