{{Rsnum
|rsid=652438
|Gene=MMP12
|Chromosome=11
|position=102865911
|Orientation=minus
|GMAF=0.1047
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(A;A)
|geno2=(A;G)
|geno3=(G;G)
|Gene_s=MMP12
}}{{ population diversity
| geno1=(A;A)
| geno2=(A;G)
| geno3=(G;G)
| CEU | 88.5 | 11.5 | 0.0
| HCB | 83.5 | 16.5 | 0.0
| JPT | 82.3 | 17.7 | 0.0
| YRI | 58.6 | 35.2 | 6.2
| ASW | 78.9 | 21.1 | 0.0
| CHB | 83.5 | 16.5 | 0.0
| CHD | 75.2 | 23.9 | 0.9
| GIH | 58.4 | 38.6 | 3.0
| LWK | 56.4 | 34.5 | 9.1
| MEX | 87.9 | 12.1 | 0.0
| MKK | 51.0 | 41.9 | 7.1
| TSI | 89.1 | 9.9 | 1.0
| HapMapRevision=28
}}{{PMID Auto
|PMID=20078883
|Title=Association of MMP - 12 polymorphisms with severe and very severe COPD: A case control study of MMPs - 1, 9 and 12 in a European population
|OA=1
}}

{{PMID Auto
|PMID=20230842
|Title=Association between polymorphisms of matrix metalloproteinase 11 (MMP-11) and Kawasaki disease in the Korean population
}}

{{PMID Auto
|PMID=21277817
|Title=Genetic variation in the matrix metalloproteinase genes and diabetic nephropathy in type 1 diabetes
|OA=1
}}

{{PMID Auto
|PMID=16311244
|Title=Genotypes and haplotypes of matrix metalloproteinase 1, 3 and 12 genes and the risk of lung cancer.
}}

{{PMID Auto
|PMID=19321798
|Title=Matrix metalloproteinase 1, 3 and 12 polymorphisms and esophageal adenocarcinoma risk and prognosis.
|OA=1
}}

{{PMID Auto
|PMID=21730350
|Title=Matrix metalloproteinase-12 (MMP-12) SNP affects MMP activity, lung macrophage infiltration and protects against emphysema in COPD.
}}

{{PMID Auto
|PMID=22388798
|Title=Gene panels to help identify subgroups at high and low risk of coronary heart disease among those randomized to antihypertensive treatment: the GenHAT study.
|OA=1
}}

{{PMID Auto
|PMID=23075521
|Title=Association Study of Matrix Metalloproteinase-12 Gene Polymorphisms and Asthma in a Japanese Population
}}

{{GET Evidence
|gene=MMP12
|aa_change=Asn356Ser
|aa_change_short=N356S
|impact=not reviewed
|qualified_impact=Insufficiently evaluated not reviewed
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs652438
|overall_frequency_n=878
|overall_frequency_d=9400
|overall_frequency=0.0934043
|n_genomes=14
|n_genomes_annotated=0
|n_haplomes=15
|n_articles=0
|n_articles_annotated=0
|nblosum100=0
|autoscore=0
|webscore=N
}}

{{PMID Auto
|PMID=23734748
|Title=Association of genes of protease-antiprotease balance pathway to lung function and emphysema subtypes
|OA=1
}}

{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | FTDNA2}}
{{on chip | FTDNA}}
{{on chip | HumanOmni1Quad}}
{{on chip | Illumina Human 1M}}