{{Rsnum
|rsid=6596075
|Gene=IBD5
|Chromosome=5
|position=132406536
|Orientation=plus
|GMAF=0.2452
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(C;C)
|geno2=(C;G)
|geno3=(G;G)
}}{{ population diversity
| geno1=(C;C)
| geno2=(C;G)
| geno3=(G;G)
| CEU | 63.7 | 36.3 | 0.0
| HCB | 77.4 | 21.2 | 1.5
| JPT | 91.2 | 8.8 | 0.0
| YRI | 15.6 | 52.4 | 32.0
| ASW | 22.8 | 57.9 | 19.3
| CHB | 77.4 | 21.2 | 1.5
| CHD | 80.7 | 19.3 | 0.0
| GIH | 69.3 | 26.7 | 4.0
| LWK | 14.5 | 44.5 | 40.9
| MEX | 70.2 | 28.1 | 1.8
| MKK | 19.2 | 44.2 | 36.5
| TSI | 70.6 | 25.5 | 3.9
| HapMapRevision=28
}}[[rs6596075]] has been reported in a large study to be associated with [[Crohn's disease]].

The risk allele (oriented to the dbSNP entry) is (C); the odds ratio associated with heterozygotes is 1.55 (CI 1.00-2.39), and for homozygotes, 2.06 (CI 1.35-3.14). {{PMID|17554300|OA=1
}}

{{omim
|desc=INFLAMMATORY BOWEL DISEASE 5; [[IBD5]]
|id=606348
|rsnum=6596075
}}

{{PMID Auto
|PMID=21061378
|Title=Two independent genetic factors responsible for the associations of the [[IBD5]] locus with [[Crohn's disease]] in the Czech population
}}

{{PMID Auto
|PMID=21674708
|Title=Two independent genetic factors responsible for the associations of the IBD5 locus with Crohn's disease in the Czech population
}}

{{PMID Auto
|PMID=18614543
|Title=The 5q31 variants associated with psoriasis and Crohn's disease are distinct.
|OA=1
}}

{{PMID Auto
|PMID=18853133
|Title=Gene variants influencing measures of inflammation or predisposing to autoimmune and inflammatory diseases are not associated with the risk of type 2 diabetes.
|OA=1
}}

{{GET Evidence
|impact=pathogenic
|qualified_impact=Insufficiently evaluated pathogenic
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs6596075
|overall_frequency_n=84
|overall_frequency_d=128
|overall_frequency=0.65625
|n_genomes=46
|n_genomes_annotated=0
|n_haplomes=70
|n_articles=0
|n_articles_annotated=0
|in_gwas=Y
|autoscore=2
|webscore=N
}}

{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | Affy GenomeWide 6}}
{{on chip | HumanOmni1Quad}}