{{Rsnum
|rsid=6596189
|Gene=PITX1
|Chromosome=5
|position=135032479
|Orientation=plus
|GMAF=0.1607
|Gene_s=LOC100996485,PITX1
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(C;C)
|geno2=(C;T)
|geno3=(T;T)
}}{{ population diversity
| geno1=(C;C)
| geno2=(C;T)
| geno3=(T;T)
| CEU | 74.3 | 23.0 | 2.7
| HCB | 100.0 | 0.0 | 0.0
| JPT | 100.0 | 0.0 | 0.0
| YRI | 33.6 | 44.5 | 21.9
| ASW | 40.4 | 50.9 | 8.8
| CHB | 100.0 | 0.0 | 0.0
| CHD | 99.1 | 0.9 | 0.0
| GIH | 94.1 | 5.9 | 0.0
| LWK | 29.6 | 50.0 | 20.4
| MEX | 79.3 | 17.2 | 3.4
| MKK | 40.6 | 43.9 | 15.5
| TSI | 84.3 | 14.7 | 1.0
| HapMapRevision=28
}}{{PMID|18053270|OA=1
}} Individuals homozygous or heterozygous for the [[rs11959298]](A)-[[rs6596189]](C) haplotype risk allele were 2.54 and 1.59 fold more likely to have [[autism]], respectively, compared to [[rs11959298]](G)-[[rs6596189]](T) carriers.

Note/caveat emptor: ~90% of the world's population carries what the authors from this for-profit genetic testing company call the "risk haplotype", yet the frequency of [[autism]] is less than 1% (perhaps 1 in 150).

{{ neighbor
| rsid = 11959298
| distance = 629
}}

{{on chip | 23andMe v1}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | FTDNA2}}
{{on chip | HumanOmni1Quad}}
{{on chip | Illumina Human 1M}}