{{Rsnum
|rsid=660339
|Gene=UCP2
|Chromosome=11
|position=73978059
|Orientation=minus
|GMAF=0.4316
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(C;C)
|geno2=(C;T)
|geno3=(T;T)
|Gene_s=UCP2
}}{{ population diversity
| geno1=(C;C)
| geno2=(C;T)
| geno3=(T;T)
| CEU | 32.7 | 50.4 | 16.8
| HCB | 32.8 | 43.8 | 23.4
| JPT | 18.6 | 51.3 | 30.1
| YRI | 27.9 | 50.3 | 21.8
| ASW | 36.8 | 40.4 | 22.8
| CHB | 32.8 | 43.8 | 23.4
| CHD | 28.7 | 54.6 | 16.7
| GIH | 45.5 | 44.6 | 9.9
| LWK | 33.6 | 58.2 | 8.2
| MEX | 32.8 | 48.3 | 19.0
| MKK | 31.4 | 55.1 | 13.5
| TSI | 41.2 | 48.0 | 10.8
| HapMapRevision=28
}}
{{PMID Auto
|PMID=19833146
|Title=Sex-specific effects of CNTF, IL6 and UCP2 polymorphisms on weight gain
}}

{{PMID|17066476}} Synergistic association of mitochondrial uncoupling protein (UCP) genes with schizophrenia.

{{PMID|17601350|OA=1
}} A genetic association analysis of cognitive ability and cognitive ageing using 325 markers for 109 genes associated with oxidative stress or cognition.

{{PMID|17894153}} Ala55Val polymorphism on UCP2 gene predicts greater weight loss in morbidly obese patients undergoing gastric banding.

{{PMID|18496642|OA=1
}} Lack of association between uncoupling protein-2 Ala55Val polymorphism and incident diabetes in the atherosclerosis risk in communities study.

{{PMID|18599530|OA=1
}} Ser1369Ala variant in sulfonylurea receptor gene ABCC8 is associated with antidiabetic efficacy of gliclazide in Chinese type 2 diabetic patients.

{{PMID|18956255}} Human uncoupling protein 2 and 3 genes are associated with obesity in Japanese.

{{PMID|18996102}} Physiogenomic comparison of edema and BMI in patients receiving rosiglitazone or pioglitazone.

{{PMID|19681913}} Polymorphisms of the UCP2 gene are associated with proliferative diabetic retinopathy in patients with diabetes mellitus.

{{PMID|19760975}} Prediction of successful weight reduction after laparoscopic adjustable gastric banding.

{{PMID|19769793|OA=1
}} Variation in the UCP2 and UCP3 genes associates with abdominal obesity and serum lipids: the Finnish Diabetes Prevention Study.

{{PMID|20142250|OA=1
}} Diabetes genes and prostate cancer in the Atherosclerosis Risk in Communities study.

{{PMID|21720911}} ESR1, FTO, and UCP2 genes interact with bariatric surgery affecting weight loss and glycemic control in severely obese patients.

{{PMID|21883184}} Polymorphisms of the UCP2 gene are associated with body fat distribution and risk of abdominal obesity in Spanish population.

{{GET Evidence
|gene=UCP2
|aa_change=Ala55Val
|aa_change_short=A55V
|impact=not reviewed
|qualified_impact=Insufficiently evaluated not reviewed
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs660339
|overall_frequency_n=4526
|overall_frequency_d=10758
|overall_frequency=0.42071
|n_genomes=35
|n_genomes_annotated=0
|n_haplomes=46
|n_articles=0
|n_articles_annotated=0
|nblosum100=2
|autoscore=0
|webscore=N
}}

{{PMID Auto
|PMID=22533685
|Title=Uncoupling protein 2 gene polymorphisms are associated with obesity
|OA=1
}}

{{PMID Auto
|PMID=23681449
|Title=Genes for Elite Power and Sprint Performance: ACTN3 Leads the Way
}}

{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | FTDNA2}}
{{on chip | HumanOmni1Quad}}
{{on chip | Illumina Human 1M}}