{{Rsnum
|rsid=664143
|Gene=ATM
|Chromosome=11
|position=108354934
|Orientation=minus
|GMAF=0.404
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(C;C)
|geno2=(C;T)
|geno3=(T;T)
|Gene_s=ATM,C11orf65
}}{{ population diversity
| geno1=(C;C)
| geno2=(C;T)
| geno3=(T;T)
| CEU | 27.4 | 54.0 | 18.6
| HCB | 22.6 | 43.8 | 33.6
| JPT | 23.9 | 41.6 | 34.5
| YRI | 46.3 | 47.6 | 6.1
| ASW | 56.1 | 29.8 | 14.0
| CHB | 22.6 | 43.8 | 33.6
| CHD | 21.1 | 51.4 | 27.5
| GIH | 51.5 | 38.6 | 9.9
| LWK | 40.9 | 47.3 | 11.8
| MEX | 37.9 | 41.4 | 20.7
| MKK | 26.9 | 50.0 | 23.1
| TSI | 54.9 | 33.3 | 11.8
| HapMapRevision=28
}}
600+ Korean [[lung cancer]] patients were part of a study that concluded that the [[rs664143]](T) allele, as oriented vis-a-vis dbSNP, located in the [[ATM]] gene and also known as IVS62+60G>A, was associated with increased risk, with an odds ratio of 1.68 (CI: 1.1-2.1, p<0.05).{{PMID|16497724}}

In a study of 119 American patients with potentially resectable [[pancreatic cancer]], the [[rs664143]](C) allele was associated with poorer overall survival (ie response) to combined gerncitabine radiation therapy. Also, as 1 of 3 SNPs its risk allele is associated with poorer overall survival for [[pancreatic cancer]] patients being treated with combined gerncitabine radiation therapy; median overall survival times of 31.0, 16.2, and 10.5 months were calculated for [[pancreatic cancer]] patients carrying < or = 1, 2, and 3 risk alleles from [[rs664143]](C), [[rs2227928]](C), and [[rs521102]](T;T), respectively (P=0.004).
{{PMID|18381943|OA=1
}}

{{PMID Auto
|PMID=21058196
|Title=Antioxidant vitamins intake, ataxia telangiectasia mutated (ATM) genetic polymorphisms, and breast cancer risk
}}

{{PMID Auto
|PMID=22203481
|Title=Association between ATM polymorphisms and cancer risk: a meta-analysis
}}

{{PMID Auto
|PMID=12466288
|Title=Haplotype and linkage disequilibrium architecture for human cancer-associated genes.
|OA=1
}}

{{PMID Auto
|PMID=17132159
|Title=Comprehensive analysis of the ATM, CHEK2 and ERBB2 genes in relation to breast tumour characteristics and survival: a population-based case-control and follow-up study.
|OA=1
}}

{{PMID Auto
|PMID=17151932
|Title=Genetic variation in p53 and ATM haplotypes and risk of glioma and meningioma.
}}

{{PMID Auto
|PMID=17431766
|Title=Two-stage case-control study of common ATM gene variants in relation to breast cancer risk.
}}

{{PMID Auto
|PMID=19115993
|Title=Association analyses of the interaction between the ADSS and ATM genes with schizophrenia in a Chinese population.
|OA=1
}}

{{PMID Auto
|PMID=19536092
|Title=Explorative study to identify novel candidate genes related to oxaliplatin efficacy and toxicity using a DNA repair array.
|OA=1
}}

{{PMID Auto
|PMID=19584272
|Title=Modification of ovarian cancer risk by BRCA1/2-interacting genes in a multicenter cohort of BRCA1/2 mutation carriers.
|OA=1
}}

{{PMID Auto
|PMID=25196645
|Title=Single nucleotide polymorphisms of ataxia telangiectasia mutated and the risk of papillary thyroid carcinoma
}}
{{on chip | 23andMe v1}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | Affy GenomeWide 6}}
{{on chip | Affy500k}}
{{on chip | FTDNA2}}
{{on chip | HumanOmni1Quad}}
{{on chip | Illumina Human 1M}}