{{Rsnum
|rsid=6661174
|Gene=FMO2
|Chromosome=1
|position=171208951
|Orientation=plus
|GMAF=0.03535
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(C;C)
|geno2=(C;T)
|geno3=(T;T)
|Gene_s=FMO2
}}{{ population diversity
| geno1=(C;C)
| geno2=(C;T)
| geno3=(T;T)
| CEU | 0.0 | 0.0 | 100.0
| HCB | 0.0 | 0.0 | 100.0
| JPT | 0.0 | 0.0 | 100.0
| YRI | 1.4 | 30.6 | 68.0
| ASW | 3.5 | 14.0 | 82.5
| CHB | 0.0 | 0.0 | 100.0
| CHD | 0.0 | 0.0 | 0.0
| GIH | 0.0 | 3.0 | 97.0
| LWK | 2.7 | 30.0 | 67.3
| MEX | 0.0 | 0.0 | 0.0
| MKK | 4.5 | 32.1 | 63.5
| TSI | 0.0 | 0.0 | 0.0
| HapMapRevision=28
}}{{PharmGKB
|RSID=rs6661174
|Name_s=g.23,238C>T, p.Q472X
|Gene_s=FMO2
|Feature=
|Evidence=PubMed ID:15864117; PubMed ID:15922018; PubMed ID:18423897
|Annotation=This variant is the defining SNP for the FMO2*1 and FMO2*2 alleles. The major allele, FMO2*2, is characterized by a T at genomic position 23,238 and encodes a truncated inactive protein. The minor allele, FMO2*1, has a C at this position and encodes a full-length active protein. Thus, this SNP could potentially be associated with differential drug response.
|Drugs=
|Drug Classes=
|Diseases=
|Curation Level=Curated
|PharmGKB Accession ID=PA161660837
}}

{{PMID Auto
|PMID=19200524
|Title=A genome-wide survey of the prevalence and evolutionary forces acting on human nonsense SNPs.
|OA=1
}}

{{PMID Auto
|PMID=19420133
|Title=Characterization of sulfoxygenation and structural implications of human flavin-containing monooxygenase isoform 2 (FMO2.1) variants S195L and N413K.
|OA=1
}}

{{PMID Auto
|PMID=21205862
|Title=Gene inactivation and its implications for annotation in the era of personal genomics.
|OA=1
}}

{{GET Evidence
|gene=FMO4
|aa_change=Stop472Gln
|aa_change_short=X472Q
|impact=not reviewed
|qualified_impact=Insufficiently evaluated not reviewed
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs6661174
|n_genomes=6
|n_genomes_annotated=0
|n_haplomes=7
|n_articles=0
|n_articles_annotated=0
|nblosum100=4
|autoscore=1
|webscore=N
}}

{{on chip | 23andMe v1}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | FTDNA2}}
{{on chip | HumanOmni1Quad}}
{{on chip | Illumina Human 1M}}