{{Rsnum
|rsid=6661946
|Gene=HEATR1
|Chromosome=1
|position=236559808
|Orientation=plus
|GMAF=0.1511
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(C;C)
|geno2=(C;T)
|geno3=(T;T)
|Gene_s=HEATR1
}}{{ population diversity
| geno1=(C;C)
| geno2=(C;T)
| geno3=(T;T)
| CEU | 94.6 | 5.4 | 0.0
| HCB | 71.3 | 27.9 | 0.7
| JPT | 64.9 | 29.7 | 5.4
| YRI | 36.7 | 51.0 | 12.2
| ASW | 58.9 | 33.9 | 7.1
| CHB | 71.3 | 27.9 | 0.7
| CHD | 78.0 | 21.1 | 0.9
| GIH | 87.1 | 12.9 | 0.0
| LWK | 33.3 | 52.8 | 13.9
| MEX | 82.1 | 17.9 | 0.0
| MKK | 25.8 | 54.2 | 20.0
| TSI | 92.2 | 7.8 | 0.0
| HapMapRevision=28
}}{{PharmGKB
|RSID=rs6661946
|Name_s=
|Gene_s=HEATR1
|Feature=
|Evidence=PubMed ID:19268276
|Annotation=In a GWAS of 3497 Dutch subjects from the Netherlands Study of Depression and Anxiety or from the Netherlands Twin Registry, this SNP was found to be associated with Current Smoking (p = 0.000004108;OR for minor allele T:2.12).
|Drugs=nicotine
|Drug Classes=
|Diseases=
|Curation Level=Curated
|PharmGKB Accession ID=PA164924497
}}

{{GET Evidence
|gene=HEATR1
|aa_change=Ser1559Asn
|aa_change_short=S1559N
|impact=pharmacogenetic
|qualified_impact=Insufficiently evaluated pharmacogenetic
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs6661946
|overall_frequency_n=1450
|overall_frequency_d=10758
|overall_frequency=0.134783
|n_genomes=17
|n_genomes_annotated=0
|n_haplomes=19
|n_articles=1
|n_articles_annotated=1
|in_pharmgkb=Y
|nblosum100=0
|autoscore=1
|webscore=N
}}

{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | Affy GenomeWide 6}}
{{on chip | FTDNA2}}
{{on chip | FTDNA}}
{{on chip | HumanOmni1Quad}}
{{on chip | Illumina Human 1M}}