{{Rsnum
|rsid = 668
|Orientation=plus
|ReferenceAllele=C
|MissenseAllele=G
|geno1=(C;C)
|geno2=(C;G)
|geno3=(G;G)
|Chromosome=17
|position=64377836
|Gene=PECAM1
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
}}{{ population diversity
| geno1=(C;C)
| geno2=(C;G)
| geno3=(G;G)
| CEU | 37.2 | 45.1 | 17.7
| HCB | 24.8 | 54.7 | 20.4
| JPT | 32.7 | 44.2 | 23.0
| YRI | 44.9 | 45.6 | 9.5
| ASW | 50.9 | 40.4 | 8.8
| CHB | 24.8 | 54.7 | 20.4
| CHD | 36.7 | 43.1 | 20.2
| GIH | 17.8 | 49.5 | 32.7
| LWK | 32.7 | 55.5 | 11.8
| MEX | 12.1 | 60.3 | 27.6
| MKK | 22.4 | 54.5 | 23.1
| TSI | 11.8 | 58.8 | 29.4
| HapMapRevision=28
}}

[http://7thspace.com/headlines/299292/variations_in_host_genes_encoding_adhesion_molecules_and_susceptibility_to_falciparum_malaria_in_india.html 7thspace]  the G allele was a risk factor for [[malaria]] in the endemic region, but exhibited significant association with protection from disease in the non-endemic region.

{{PMID Auto
|PMID=19055786
|Title=Variations in host genes encoding adhesion molecules and susceptibility to falciparum malaria in India.
|OA=1
}}

{{PMID Auto
|PMID=19406964
|Title=Association of genetic variants with chronic kidney disease in Japanese individuals.
|OA=1
}}

{{PMID Auto
|PMID=20031567
|Title=An evaluation of candidate genes of inflammation and thrombosis in relation to the risk of venous thromboembolism: The Women's Genome Health Study.
|OA=1
}}

{{PMID Auto
|PMID=21155722
|Title=Minor histocompatibility antigens in Tunisians: could platelet endothelial cell adhesion molecule 1 marker be one of them?
}}

{{GET Evidence
|gene=PECAM1
|aa_change=Leu125Val
|aa_change_short=L125V
|impact=pharmacogenetic
|qualified_impact=Low clinical importance, Likely pharmacogenetic
|inheritance=other
|quality_scores=Array
|dbsnp_id=rs668
|overall_frequency_n=73
|overall_frequency_d=128
|overall_frequency=0.570312
|n_genomes=45
|n_genomes_annotated=0
|n_haplomes=63
|n_articles=1
|n_articles_annotated=1
|qualityscore_in_silico=1
|qualitycomment_in_silico=Y
|qualityscore_in_vitro=0
|qualityscore_case_control=4
|qualitycomment_case_control=Y
|qualityscore_familial=0
|qualityscore_severity=3
|qualitycomment_severity=Y
|qualityscore_treatability=4
|qualitycomment_treatability=Y
|in_omim=Y
|nblosum100=0
|autoscore=2
|webscore=N
|variant_evidence=0
|clinical_importance=1
|summary_short=Mismatched genotypes in this variant between donor and recipient is associated with causing graft vs. host disease in bone marrow transplants.
}}

{{PMID Auto
|PMID=23906939
|Title=Association of single nucleotide polymorphisms in the gene encoding platelet endothelial cell adhesion molecule-1 with the risk of myocardial infarction: a systematic review and meta-analysis
}}

{{PMID Auto
|PMID=23906684
|Title=Genetic associations with coronary heart disease: Meta-analyses of 12 candidate genetic variants
}}

{{PMID Auto
|PMID=22646485
|Title=Association between genetic variants in adhesion molecules and outcomes after hematopoietic cell transplants
|OA=1
}}

{{on chip | 23andMe v1}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | Affy GenomeWide 6}}