{{Rsnum
|rsid=6684439
|Gene=IL6R
|Chromosome=1
|position=154423363
|Orientation=plus
|GMAF=0.3815
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(C;C)
|geno2=(C;T)
|geno3=(T;T)
|Gene_s=IL6R
}}{{ population diversity
| geno1=(C;C)
| geno2=(C;T)
| geno3=(T;T)
| CEU | 43.4 | 44.2 | 12.4
| HCB | 33.6 | 51.1 | 15.3
| JPT | 42.5 | 42.5 | 15.0
| YRI | 36.7 | 49.7 | 13.6
| ASW | 40.4 | 43.9 | 15.8
| CHB | 33.6 | 51.1 | 15.3
| CHD | 33.0 | 44.0 | 22.9
| GIH | 46.5 | 47.5 | 5.9
| LWK | 46.4 | 48.2 | 5.5
| MEX | 29.3 | 39.7 | 31.0
| MKK | 62.8 | 33.3 | 3.8
| TSI | 36.3 | 50.0 | 13.7
| HapMapRevision=28
}}A study of 219 female [[melanoma]] patients and an equal number of controls concluded that 4 linked SNPs within the [[IL6R]] gene were associated with increased [[melanoma]] risk, but only when heterozygous. [Note that there may have been too few minor allele homozygotes to study, though.] The odds ratio associated with the minor allele of this SNP, [[rs6684439]], was 1.74 (CI: 1.07-2.81). The 4 linked SNPs from identified in this study are: [[rs6684439]], [[rs4845618]], [[rs4845622]], and [[rs8192284]].{{PMID|18781131|OA=1
}}

{{PMID Auto
|PMID=18852330
|Title=Interleukin-6 receptor gene, plasma C-reactive protein, and diabetes risk in women.
|OA=1
}}

{{PMID Auto
|PMID=19124510
|Title=Insulin-like growth factor-1- and interleukin-6-related gene variation and risk of multiple myeloma.
|OA=1
}}

{{PMID Auto
|PMID=20031577
|Title=Novel loci, including those related to Crohn disease, psoriasis, and inflammation, identified in a genome-wide association study of fibrinogen in 17 686 women: the Women's Genome Health Study.
|OA=1
}}

{{on chip | 23andMe v1}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | Illumina Human 1M}}