{{Rsnum
|rsid=6684865
|Gene=MMEL1
|Chromosome=1
|position=2614790
|Orientation=plus
|GMAF=0.4178
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(A;A)
|geno2=(A;G)
|geno3=(G;G)
|Gene_s=MMEL1
}}{{ population diversity
| geno1=(A;A)
| geno2=(A;G)
| geno3=(G;G)
| CEU | 12.4 | 41.6 | 46.0
| HCB | 22.6 | 58.4 | 19.0
| JPT | 22.1 | 52.2 | 25.7
| YRI | 32.0 | 50.3 | 17.7
| ASW | 26.3 | 49.1 | 24.6
| CHB | 22.6 | 58.4 | 19.0
| CHD | 27.5 | 54.1 | 18.3
| GIH | 19.8 | 49.5 | 30.7
| LWK | 30.9 | 45.5 | 23.6
| MEX | 15.5 | 46.6 | 37.9
| MKK | 28.2 | 48.1 | 23.7
| TSI | 4.9 | 41.2 | 53.9
| HapMapRevision=28
}}[[rs6684865]] has been reported in a large study to be associated with [[rheumatoid arthritis]].

The risk allele (oriented to the dbSNP entry) is (G); the odds ratio associated with heterozygotes is 1.27 (CI 1.02-1.56), and for homozygotes, 1.54 (CI 1.25-1.90). {{PMID|17554300|OA=1
}}

{{PMID Auto
|PMID=20187130
|Title=Evidence of epistasis between TNFRSF14 and TNFRSF6B polymorphisms in patients with rheumatoid arthritis
}}

{{PMID Auto
|PMID=20962851
|Title=Members 6B and 14 of the TNF receptor superfamily in multiple sclerosis predisposition
}}

{{PMID Auto
|PMID=18794857
|Title=Rheumatoid arthritis susceptibility loci at chromosomes 10p15, 12q13 and 22q13.
|OA=1
}}

{{PMID Auto
|PMID=20017963
|Title=Representation of genetic association via attributable familial relative risks in order to identify polymorphisms functionally relevant to rheumatoid arthritis.
|OA=1
}}

{{PMID Auto
|PMID=20439292
|Title=Genetic variants in the prediction of rheumatoid arthritis.
}}

{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | Affy GenomeWide 6}}
{{on chip | FTDNA2}}
{{on chip | HumanOmni1Quad}}
{{on chip | Illumina Human 1M}}