{{Rsnum
|rsid=6700125
|Chromosome=1
|position=59237125
|Orientation=plus
|GMAF=0.444
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(C;C)
|geno2=(C;T)
|geno3=(T;T)
}}{{ population diversity
| geno1=(C;C)
| geno2=(C;T)
| geno3=(T;T)
| CEU | 52.2 | 36.3 | 11.5
| HCB | 23.4 | 56.2 | 20.4
| JPT | 28.3 | 45.1 | 26.5
| YRI | 11.6 | 40.8 | 47.6
| ASW | 19.3 | 54.4 | 26.3
| CHB | 23.4 | 56.2 | 20.4
| CHD | 25.7 | 45.9 | 28.4
| GIH | 33.7 | 40.6 | 25.7
| LWK | 9.2 | 41.3 | 49.5
| MEX | 63.8 | 32.8 | 3.4
| MKK | 5.1 | 37.2 | 57.7
| TSI | 43.1 | 47.1 | 9.8
| HapMapRevision=28
}}[[rs6700125]] is one of 6 SNPs found upstream of an (uncharacterized) gene known as FLJ10986 that have been found to be overrepresented in patients with sporadic amyotrophic lateral sclerosis ([[ALS]]). 

A genome-wide association study of 1,152 [[ALS]] patients determined an allelic odds ratio of 1.38 for the [[rs6700125]](T) allele (CI: 1.16-1.65, p=0.00032). The genotypic odds ratio presented were 1.76 (CI: 1.22-2.55) and 1.2 (CI: 0.83-1.73) for homozygotes and heterozygotes, respectively.{{PMID|17671248}}

* Note: this SNP is in strong linkage disequilibrium with [[rs6690993]] (r<sup>2</sup>>0.8)

{{PMID|19177248}} A study involving a large case-control series from the Netherlands, Belgium, Sweden and Ireland (total: 1883 sporadic ALS patients and 2063 controls) found no significant association between sporadic ALS and the six previously reported associated SNPs, including this one.

{{PMID Auto
|PMID=19922138
|Title=Analysis of FGGY as a risk factor for sporadic amyotrophic lateral sclerosis
}}

{{PMID Auto
|PMID=19193627
|Title=A two-stage genome-wide association study of sporadic amyotrophic lateral sclerosis.
|OA=1
}}

{{PMID Auto
|PMID=22795786
|Title=No association of five candidate genetic variants with amyotrophic lateral sclerosis in a Chinese population
}}

{{PMID Auto
|PMID=24439956
|Title=The single-nucleotide polymorphism rs6690993 in FGGY is not associated with amyotrophic lateral sclerosisin a large Chinese cohort
}}
{{on chip | 23andMe v1}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | FTDNA2}}
{{on chip | FTDNA}}
{{on chip | HumanOmni1Quad}}
{{on chip | Illumina Human 1M}}