{{Rsnum
|rsid=6709476
|Gene=TCF7L1
|Chromosome=2
|position=85216801
|Orientation=plus
|GMAF=0.2466
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(A;A)
|geno2=(A;G)
|geno3=(G;G)
|Gene_s=LOC102724579,TCF7L1
}}{{ population diversity
| geno1=(A;A)
| geno2=(A;G)
| geno3=(G;G)
| CEU | 1.8 | 10.6 | 87.6
| HCB | 0.7 | 13.1 | 86.1
| JPT | 0.9 | 9.7 | 89.4
| YRI | 62.6 | 33.3 | 4.1
| ASW | 54.4 | 40.4 | 5.3
| CHB | 0.7 | 13.1 | 86.1
| CHD | 1.8 | 23.9 | 74.3
| GIH | 0.0 | 16.8 | 83.2
| LWK | 50.9 | 39.1 | 10.0
| MEX | 6.9 | 29.3 | 63.8
| MKK | 29.5 | 53.2 | 17.3
| TSI | 2.0 | 14.7 | 83.3
| HapMapRevision=28
}}{{PharmGKB
|RSID=rs6709476
|Name_s=
|Gene_s=TCF7L1
|Feature=
|Evidence=PubMed ID:19268276
|Annotation=In a GWAS of 3497 Dutch subjects from the Netherlands Study of Depression and Anxiety or from the Netherlands Twin Registry, this SNP was found to be associated with Current Smoking (p = 0.00005569;OR for minor allele A:1.42).
|Drugs=nicotine
|Drug Classes=
|Diseases=
|Curation Level=Curated
|PharmGKB Accession ID=PA164924498
}}

{{GET Evidence
|impact=pharmacogenetic
|qualified_impact=Insufficiently evaluated pharmacogenetic
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs6709476
|overall_frequency_n=37
|overall_frequency_d=128
|overall_frequency=0.289062
|n_genomes=25
|n_genomes_annotated=0
|n_haplomes=37
|n_articles=1
|n_articles_annotated=0
|in_pharmgkb=Y
|autoscore=1
|webscore=N
}}

{{on chip | 23andMe v1}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | Affy GenomeWide 6}}
{{on chip | FTDNA2}}
{{on chip | HumanOmni1Quad}}
{{on chip | Illumina Human 1M}}