{{Rsnum
|rsid=6742078
|Gene=UGT1A10
|Chromosome=2
|position=233763993
|Orientation=plus
|ReferenceAllele=G
|MissenseAllele=T
|GMAF=0.3035
|Gene_s=UGT1A1,UGT1A3,UGT1A4,UGT1A5,UGT1A6,UGT1A7,UGT1A8,UGT1A9,UGT1A10
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(G;G)
|geno2=(G;T)
|geno3=(T;T)
}}{{ population diversity
| geno1=(G;G)
| geno2=(G;T)
| geno3=(T;T)
| CEU | 45.1 | 46.9 | 8.0
| HCB | 75.9 | 22.6 | 1.5
| JPT | 70.8 | 23.9 | 5.3
| YRI | 29.0 | 47.6 | 23.4
| ASW | 22.8 | 63.2 | 14.0
| CHB | 75.9 | 22.6 | 1.5
| CHD | 72.2 | 25.9 | 1.9
| GIH | 34.7 | 43.6 | 21.8
| LWK | 22.2 | 62.0 | 15.7
| MEX | 44.8 | 48.3 | 6.9
| MKK | 27.7 | 49.7 | 22.6
| TSI | 51.0 | 40.2 | 8.8
| HapMapRevision=28
}}{{PMID Auto GWAS
|PMID=19414484
|Trait=Serum bilirubin levels
|Title=Genome-wide association meta-analysis for total serum bilirubin levels
|RiskAllele=T
|Pval=0
|OR=0.23
|ORtxt=[0.21-0.25] umol/l increase in log(tbil)
|OA=1
}}

{{PMID Auto
|PMID=20837016
|Title=Loci from a genome-wide analysis of bilirubin levels are associated with gallstone risk and composition
}}

{{omim
|id=191740
|desc=UDP-GLYCOSYLTRANSFERASE 1 FAMILY, POLYPEPTIDE A1; UGT1A1
|rsnum=6742078
}}

{{omim
|id=191740
|rsnum=6742078
|variant=0025
}}

{{omim
|id=601816
|rsnum=6742078
}}

{{PMID Auto
|PMID=21412181
|Title=Genetic variation in UGT1A1 typical of [[Gilbert syndrome]] is associated with unconjugated hyperbilirubinemia in patients receiving tocilizumab
}}

{{PMID Auto GWAS
|PMID=22511988
|Trait=None
|Title=A genome-wide association study identifies UGT1A1 as a regulator of serum cell-free DNA in young adults: The Cardiovascular Risk in Young Finns Study.
|RiskAllele=T
|Pval=2E-23
|OR=0.3358
|ORtxt=None
|OA=1
}}

{{PMID|19223546|OA=1
}} Xenobiotic metabolizing gene variants, dietary heterocyclic amine intake, and risk of prostate cancer.

{{PMID|19482841|OA=1
}} Serum bilirubin levels on ICU admission are associated with ARDS development and mortality in sepsis.

{{GET Evidence
|impact=pathogenic
|qualified_impact=Insufficiently evaluated pathogenic
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs6742078
|overall_frequency_n=48
|overall_frequency_d=128
|overall_frequency=0.375
|n_genomes=38
|n_genomes_annotated=0
|n_haplomes=44
|n_articles=0
|n_articles_annotated=0
|in_gwas=Y
|autoscore=1
|webscore=N
}}

{{PMID Auto
|PMID=23753274
|Title=Extreme bilirubin levels as a causal risk factor for symptomatic gallstone disease
}}

{{PMID Auto
|PMID=23371916
|Title=A Genome-Wide Association Study for Serum Bilirubin Levels and Gene-Environment Interaction in a Chinese Population
}}

{{PMID Auto
|PMID=22805420
|Title=Genetically elevated bilirubin and risk of ischaemic heart disease: three Mendelian randomization studies and a meta-analysis
}}

{{on chip | 23andMe v1}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | Affy GenomeWide 6}}
{{on chip | HumanOmni1Quad}}
{{on chip | Illumina Human 1M}}