{{Rsnum
|rsid=6754295
|Chromosome=2
|position=20983311
|Orientation=plus
|GMAF=0.3751
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(G;G)
|geno2=(G;T)
|geno3=(T;T)
}}{{ population diversity
| geno1=(G;G)
| geno2=(G;T)
| geno3=(T;T)
| CEU | 6.2 | 30.1 | 63.7
| HCB | 49.6 | 42.3 | 8.0
| JPT | 46.9 | 41.6 | 11.5
| YRI | 7.5 | 36.7 | 55.8
| ASW | 3.5 | 47.4 | 49.1
| CHB | 49.6 | 42.3 | 8.0
| CHD | 54.2 | 35.5 | 10.3
| GIH | 30.7 | 51.5 | 17.8
| LWK | 4.5 | 43.6 | 51.8
| MEX | 3.4 | 41.4 | 55.2
| MKK | 5.8 | 28.8 | 65.4
| TSI | 7.8 | 43.1 | 49.0
| HapMapRevision=28
}}
{{PMID Auto GWAS
|PMID=19060911
|Trait=HDL cholesterol
|Title=Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts
|RiskAllele=C
|Pval=4E-8
|OR=0.07
|ORtxt=[NR] SD increase
|OA=1
}}

{{PharmGKB
|RSID=rs6754295
|Name_s=
|Gene_s=-
|Feature=
|Evidence=PubMed ID:19060911; Web Resource:http://www.genome.gov/gwastudies/
|Annotation=GWAS results: Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts. (Initial Sample Size: 17,815 individuals; Replication Sample Size: NR); (Region: 2p24.1; Reported Gene(s): APOB; Risk Allele: rs6754295-C); (p-value= 0.00000003).This variant is associated with Triglycerides.
|Drugs=
|Drug Classes=
|Diseases=
|Curation Level=Non-Curated
|PharmGKB Accession ID=PA164740232
}}

{{PharmGKB
|RSID=rs6754295
|Name_s=
|Gene_s=-
|Feature=
|Evidence=PubMed ID:19060911; Web Resource:http://www.genome.gov/gwastudies/
|Annotation=GWAS results: Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts. (Initial Sample Size: 21,412 individuals; Replication Sample Size: NR); (Region: 2p24.1; Reported Gene(s): APOB; Risk Allele: rs6754295-C); (p-value= 0.00000004).This variant is associated with HDL cholesterol.
|Drugs=
|Drug Classes=
|Diseases=
|Curation Level=Non-Curated
|PharmGKB Accession ID=PA164740205
}}

{{PMID Auto
|PMID=19041386
|Title=Genetic-epidemiological evidence on genes associated with HDL cholesterol levels: a systematic in-depth review.
|OA=1
}}

{{PMID Auto
|PMID=19951432
|Title=Analysis of recently identified dyslipidemia alleles reveals two loci that contribute to risk for carotid artery disease.
|OA=1
}}

{{PMID Auto
|PMID=20502693
|Title=Genetics and beyond--the transcriptome of human monocytes and disease susceptibility.
|OA=1
}}

{{GET Evidence
|impact=pathogenic
|qualified_impact=Insufficiently evaluated pathogenic
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs6754295
|overall_frequency_n=90
|overall_frequency_d=128
|overall_frequency=0.703125
|n_genomes=48
|n_genomes_annotated=0
|n_haplomes=75
|n_articles=0
|n_articles_annotated=0
|in_gwas=Y
|in_pharmgkb=Y
|autoscore=2
|webscore=N
}}

{{on chip | 23andMe v1}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | Illumina Human 1M}}