{{Rsnum
|rsid=6795970
|Gene=SCN10A
|Chromosome=3
|position=38725184
|Orientation=plus
|GMAF=0.264
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(A;A)
|geno2=(A;G)
|geno3=(G;G)
|Gene_s=SCN10A
}}{{ population diversity
| geno1=(A;A)
| geno2=(A;G)
| geno3=(G;G)
| CEU | 14.2 | 55.8 | 30.1
| HCB | 2.2 | 26.3 | 71.5
| JPT | 3.5 | 31.9 | 64.6
| YRI | 0.0 | 1.4 | 98.6
| ASW | 3.5 | 15.8 | 80.7
| CHB | 2.2 | 26.3 | 71.5
| CHD | 2.8 | 22.9 | 74.3
| GIH | 10.9 | 50.5 | 38.6
| LWK | 0.0 | 10.9 | 89.1
| MEX | 7.0 | 40.4 | 52.6
| MKK | 0.6 | 18.7 | 80.6
| TSI | 16.7 | 49.0 | 34.3
| HapMapRevision=28
}}{{PMID Auto
|PMID=20062061
|Title=Genetic variation in SCN10A influences cardiac conduction
}}

{{PMID Auto GWAS
|PMID=20062063
|Trait=Electrocardiographic traits
|Title=Several common variants modulate heart rate, PR interval and QRS duration
|RiskAllele=A
|Pval=4E-9
|OR=5.17
|ORtxt=[3.46-6.89] % SD increase
}}

{{PMID Auto
|PMID=21041692
|Title=Identification of genomic predictors of atrioventricular conduction: using electronic medical records as a tool for genome science
|OA=1
}}

{{PMID Auto
|PMID=20062060
|Title=Genome-wide association study of PR interval.
|OA=1
}}

{{PMID Auto
|PMID=21347284
|Title=Genome-wide association studies of the PR interval in African Americans.
|OA=1
}}

{{GET Evidence
|gene=SCN10A
|aa_change=Val1073Ala
|aa_change_short=V1073A
|impact=not reviewed
|qualified_impact=Insufficiently evaluated not reviewed
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs6795970
|overall_frequency_n=7559
|overall_frequency_d=10758
|overall_frequency=0.70264
|n_genomes=53
|n_genomes_annotated=0
|n_haplomes=92
|n_articles=0
|n_articles_annotated=0
|nblosum100=2
|autoscore=0
|webscore=N
}}

{{PMID Auto GWAS
  |PMID=23463857
  |Trait=Electrocardiographic conduction measures
  |Title=Genome- and phenome-wide analyses of cardiac conduction identifies markers of arrhythmia risk.
  |RiskAllele=A
  |Pval=5E-27
  |OR=.75
  |ORtxt=[NR] msec increase
  |OA=1
}}

{{PMID Auto
|PMID=24072447
|Title=Common SCN10A variants modulate PR interval and heart rate response during atrial fibrillation
}}

{{PMID Auto
|PMID=23092954
|Title=SHAVE: shrinkage estimator measured for multiple visits increases power in GWAS of quantitative traits.
|OA=1
}}

{{PMID Auto
|PMID=25085921
|Title=Common and Rare Variants in SCN10A Modulate the Risk of Atrial Fibrillation
}}
{{on chip | 23andMe v1}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | HumanOmni1Quad}}
{{on chip | Illumina Human 1M}}