{{Rsnum
|rsid=6808874
|Gene=GSK3B
|Chromosome=3
|position=119839004
|Orientation=plus
|GMAF=0.2929
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(A;A)
|geno2=(A;T)
|geno3=(T;T)
|Gene_s=GSK3B
}}{{ population diversity
| geno1=(A;A)
| geno2=(A;T)
| geno3=(T;T)
| CEU | 89.2 | 10.8 | 0.0
| HCB | 20.0 | 62.2 | 17.8
| JPT | 22.7 | 54.5 | 22.7
| YRI | 41.3 | 46.0 | 12.7
| ASW | 0.0 | 0.0 | 0.0
| CHB | 20.0 | 62.2 | 17.8
| CHD | 0.0 | 0.0 | 0.0
| GIH | 0.0 | 0.0 | 0.0
| LWK | 0.0 | 0.0 | 0.0
| MEX | 0.0 | 0.0 | 0.0
| MKK | 0.0 | 0.0 | 0.0
| TSI | 0.0 | 0.0 | 0.0
| HapMapRevision=28
}}{{PharmGKB
|RSID=rs6808874
|Name_s=GSK3B: IVS11+4251 T>A
|Gene_s=GSK3B
|Feature=
|Evidence=PubMed ID:18195730
|Annotation=This variant is associated with antidepressant treatment response in Chinese major depressive disorder. In a four-locus haplotype analysis (rs334558; rs13321783; rs2319398; rs6808874), the GSK3B TAGT carriers showed a poorer response to antidepressants than carriers with other haplotype groups.
|Drugs=citalopram; fluoxetine
|Drug Classes=
|Diseases=Depression; Depressive Disorder, Major
|Curation Level=Curated
|PharmGKB Accession ID=PA162369931
}}

{{PMID Auto
|PMID=18195729
|Title=Glycogen synthase kinase-3beta gene is associated with antidepressant treatment response in Chinese major depressive disorder.
}}

{{GET Evidence
|impact=pharmacogenetic
|qualified_impact=Insufficiently evaluated pharmacogenetic
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs6808874
|overall_frequency_n=31
|overall_frequency_d=128
|overall_frequency=0.242188
|n_genomes=26
|n_genomes_annotated=0
|n_haplomes=32
|n_articles=1
|n_articles_annotated=0
|in_pharmgkb=Y
|autoscore=1
|webscore=N
}}

{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}