{{Rsnum
|rsid=6812193
|Gene=FAM47E
|Chromosome=4
|position=76277833
|Orientation=plus
|GMAF=0.3007
|Gene_s=FAM47E,FAM47E-STBD1
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(C;C)
|geno2=(C;T)
|geno3=(T;T)
}}{{ population diversity
| geno1=(C;C)
| geno2=(C;T)
| geno3=(T;T)
| CEU | 34.5 | 51.3 | 14.2
| HCB | 79.6 | 18.2 | 2.2
| JPT | 84.1 | 14.2 | 1.8
| YRI | 29.3 | 55.1 | 15.6
| ASW | 26.3 | 52.6 | 21.1
| CHB | 79.6 | 18.2 | 2.2
| CHD | 83.5 | 14.7 | 1.8
| GIH | 50.5 | 45.5 | 4.0
| LWK | 29.4 | 47.7 | 22.9
| MEX | 63.8 | 29.3 | 6.9
| MKK | 28.2 | 52.6 | 19.2
| TSI | 30.4 | 53.9 | 15.7
| HapMapRevision=28
}}

People with two copies of the T allele at [[rs6812193]] appear to have a slightly lower risk of [[Parkinson's disease]]. {{PMID|21738487|OA=1
}}

The same researchers identified another risk allele for Parkinson's disease at [[rs11868035]]. [http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1002141 plos]

{{PMID Auto GWAS
|PMID=19915575
|Trait=Parkinson's disease
|Title=Genome-wide association study reveals genetic risk underlying Parkinson's disease
|RiskAllele=T
|Pval=4E-7
|OR=1.12
|ORtxt=[NR]
|OA=1
}}

{{PMID Auto
|PMID=22531747
|Title=Association study between two novel single nucleotide polymorphisms and sporadic Parkinson's disease in Chinese Han population
}}

{{PMID Auto
|PMID=22465138
|Title=Association study of SCARB2 rs6812193 polymorphism with Parkinson's disease in Han Chinese.
}}

{{GET Evidence
|impact=pathogenic
|qualified_impact=Insufficiently evaluated pathogenic
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs6812193
|overall_frequency_n=49
|overall_frequency_d=128
|overall_frequency=0.382812
|n_genomes=34
|n_genomes_annotated=0
|n_haplomes=45
|n_articles=0
|n_articles_annotated=0
|in_gwas=Y
|autoscore=1
|webscore=N
}}

{{PMID Auto
|PMID=23419877
|Title=Is Parkinson disease associated with lysosomal integral membrane protein type-2?: Challenges in interpreting association data
|OA=1
}}

{{PMID Auto
|PMID=23473716
|Title=Association study of rs6812193 polymorphism with Parkinson's disease in a Greek population
}}

{{PMID Auto
|PMID=23408458
|Title=The role of SCARB2 as susceptibility factor in Parkinson's disease
}}

{{on chip | 23andMe v1}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | HumanOmni1Quad}}
{{on chip | Illumina Human 1M}}