{{Rsnum
|rsid=684513
|Gene=CHRNA5
|Chromosome=15
|position=78566058
|Orientation=plus
|GMAF=0.2456
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(C;C)
|geno2=(C;G)
|geno3=(G;G)
|Gene_s=CHRNA5
}}{{ population diversity
| geno1=(C;C)
| geno2=(C;G)
| geno3=(G;G)
| CEU | 61.5 | 35.4 | 3.1
| HCB | 51.1 | 42.2 | 6.7
| JPT | 52.3 | 47.7 | 0.0
| YRI | 69.8 | 30.2 | 0.0
| ASW | 0.0 | 0.0 | 0.0
| CHB | 51.1 | 42.2 | 6.7
| CHD | 0.0 | 0.0 | 0.0
| GIH | 0.0 | 0.0 | 0.0
| LWK | 0.0 | 0.0 | 0.0
| MEX | 0.0 | 0.0 | 0.0
| MKK | 0.0 | 0.0 | 0.0
| TSI | 0.0 | 0.0 | 0.0
| HapMapRevision=28
}}{{PMID Auto
|PMID=20554942
|Title=Nicotinic Acetylcholine Receptor Region on Chromosome 15q25 and Lung Cancer Risk Among African Americans: A Case-Control Study
|OA=1
}}

{{PMID|17135278|OA=1
}} Cholinergic nicotinic receptor genes implicated in a nicotine dependence association study targeting 348 candidate genes with 3713 SNPs.

{{PMID|17373692|OA=1
}} No evidence for association between 19 cholinergic genes and bipolar disorder.

{{PMID|18163978|OA=1
}} The CHRNA5/A3/B4 gene cluster variability as an important determinant of early alcohol and tobacco initiation in young adults.

{{PMID|18165968|OA=1
}} Identification of pharmacogenetic markers in smoking cessation therapy.

{{PMID|18519524|OA=1
}} Variants in nicotinic receptors and risk for nicotine dependence.

{{PMID|18571741|OA=1
}} Genetic variability in nicotinic acetylcholine receptors and nicotine addiction: converging evidence from human and animal research.

{{PMID|19029397|OA=1
}} Nicotinic receptor gene variants influence susceptibility to heavy smoking.

{{PMID|19443489|OA=1
}} Risk for nicotine dependence and lung cancer is conferred by mRNA expression levels and amino acid change in CHRNA5.

{{PMID|20485328|OA=1
}} Variation in nicotinic acetylcholine receptor genes is associated with multiple substance dependence phenotypes.

{{PMID|20700436|OA=1
}} Multiple independent loci at chromosome 15q25.1 affect smoking quantity: a meta-analysis and comparison with lung cancer and COPD.

{{PMID|20886544}} Risk gene variants for nicotine dependence in the CHRNA5-CHRNA3-CHRNB4 cluster are associated with cognitive performance.

{{PMID|21430647|OA=1
}} The galanin receptor 1 gene associates with tobacco craving in smokers seeking cessation treatment.

{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}