{{Rsnum
|rsid=6855911
|Gene=SLC2A9
|Chromosome=4
|position=9934286
|Orientation=plus
|GMAF=0.2567
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(A;A)
|geno2=(A;G)
|geno3=(G;G)
|Gene_s=SLC2A9
}}{{ population diversity
| geno1=(A;A)
| geno2=(A;G)
| geno3=(G;G)
| CEU | 44.6 | 49.2 | 6.2
| HCB | 97.8 | 2.2 | 0.0
| JPT | 97.8 | 2.2 | 0.0
| YRI | 28.6 | 54.0 | 17.5
| ASW | 26.3 | 54.4 | 19.3
| CHB | 97.8 | 2.2 | 0.0
| CHD | 91.7 | 8.3 | 0.0
| GIH | 61.4 | 34.7 | 4.0
| LWK | 22.0 | 56.9 | 21.1
| MEX | 45.6 | 40.4 | 14.0
| MKK | 32.7 | 57.7 | 9.6
| TSI | 52.0 | 43.1 | 4.9
| HapMapRevision=28
}}{{PMID|17997608|OA=1
}} risk for cardiovascular morbidity and mortality [[rs6855911]] (p = 1.84E-16)

{{PMID|18398472|OA=1
}} although no risk for coronary artery disease or myocardial infarction was observed, [[rs6855911]] was associated with [[gout]]. The minor allele had a protective effect, with an allelic odds ratio of 0.62 (CI: 0.52-0.75, p = 3.2x10(-7)).

{{GWAS Summary
|SNP=rs6855911
|PubMedID=17997608
|Condition=Serum urate
|Gene=GLUT9
|Risk Allele=A
|pValue=2.00E-016
|OR=0.32
|95CI=NR) mg/dl highe
|OA=1
}}

{{PMID Auto
|PMID=19890391
|Title=Common polymorphisms influencing serum uric Acid levels contribute to susceptibility to gout, but not to coronary artery disease
|OA=1
}}

{{PharmGKB
|RSID=rs6855911
|Name_s=
|Gene_s=SLC2A9
|Feature=
|Evidence=PubMed ID:17997608; Web Resource:http://www.genome.gov/gwastudies/
|Annotation=GWAS Results: The GLUT9 Gene Is Associated with Serum Uric Acid Levels in Sardinia and Chianti Cohorts (Initial Sample Size: 4,305 Sardinian individuals; Replication Sample Size: 1,301 Tuscan individuals; Risk Allele: rs6855911-A). This variant is associated with serum urate levels.
|Drugs=
|Drug Classes=
|Diseases=Cardiovascular Diseases
|Curation Level=Non-Curated
|PharmGKB Accession ID=PA162356697
}}

{{PMID Auto
|PMID=18487473
|Title=Sex-specific association of the putative fructose transporter SLC2A9 variants with uric acid levels is modified by BMI.
|OA=1
}}

{{PMID Auto
|PMID=18606621
|Title=SLC2A9--a fructose transporter identified as a novel uric acid transporter.
|OA=1
}}

{{PMID Auto
|PMID=18852197
|Title=Metabolic and cardiovascular traits: an abundance of recently identified common genetic variants.
|OA=1
}}

{{PMID Auto
|PMID=19679263
|Title=Using new tools to define the genetic underpinnings of risky traits associated with coronary artery disease: the SardiNIA study.
|OA=1
}}

{{PMID Auto
|PMID=20053405
|Title=Sex and age interaction with genetic association of atherogenic uric acid concentrations.
|OA=1
}}

{{PMID Auto
|PMID=20972595
|Title=Association of an intronic SNP of SLC2A9 gene with serum uric acid levels in the Chinese male Han population by high-resolution melting method.
}}

{{GET Evidence
|impact=pathogenic
|qualified_impact=Insufficiently evaluated pathogenic
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs6855911
|overall_frequency_n=42
|overall_frequency_d=128
|overall_frequency=0.328125
|n_genomes=36
|n_genomes_annotated=0
|n_haplomes=42
|n_articles=0
|n_articles_annotated=0
|in_gwas=Y
|in_pharmgkb=Y
|autoscore=2
|webscore=N
}}

{{PMID Auto
|PMID=22723994
|Title=Serum uric acid and adiposity: deciphering causality using a bidirectional Mendelian randomization approach
|OA=1
}}

{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | Affy GenomeWide 6}}
{{on chip | HumanOmni1Quad}}