{{Rsnum
|rsid=689465
|Gene=PTGS2
|Chromosome=1
|position=186681714
|Orientation=minus
|GMAF=0.1171
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(A;A)
|geno2=(A;G)
|geno3=(G;G)
|Gene_s=PTGS2
}}[[rs689465]] is a SNP in the [[PTGS2]] gene, also known as COX-2, that has been associated with increased risk for mild [[asthma]] based on a study of 663 Australian patients. The odds ratio for mild asthma associated with (A;A) genotypes was 1.5 (CI: 1.12-2.02, p=0.02).{{PMID|18489027}}
{{ neighbor
| rsid = 20417
| distance = 525
}}
{{ neighbor
| rsid = 20415
| distance = 159
}}

{{PMID|18085997}} Pyrosequencing of polymorphisms in the COX-2 gene (PTGS2) with reported clinical relevance.

{{PMID|21304218}} Cyclooxygenase-2 polymorphisms and susceptibility to esophageal cancer: a meta-analysis.

{{PMID|21538574}} Interaction of cyclooxygenase-2 promoter polymorphisms with Helicobacter pylori infection and risk of gastric cancer.

{{PMID|21848701}} Functional genetic variations of cyclooxygenase-2 and susceptibility to acute myeloid leukemia in a Chinese population.

{{PMID|22037828}} Polymorphisms in cycloxygenase-2 gene and breast cancer prognosis: association between PTGS2 haplotypes and histopathological features.

{{PMID Auto
|PMID=24789723
|Title=Cyclooxygenase-2 Polymorphisms and Breast Cancer Associated Risk in Pakistani Patients
}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | FTDNA2}}
{{on chip | HumanOmni1Quad}}