{{Rsnum
|rsid=689469
|Gene=PTGS2
|Chromosome=1
|position=186672065
|Orientation=minus
|GMAF=0.008724
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(A;A)
|geno2=(A;G)
|geno3=(G;G)
|Gene_s=PTGS2
}}{{ population diversity
| geno1=(A;A)
| geno2=(A;G)
| geno3=(G;G)
| CEU | 0.0 | 3.6 | 96.4
| HCB | 0.0 | 0.0 | 0.0
| JPT | 0.0 | 0.0 | 0.0
| YRI | 0.0 | 0.7 | 99.3
| ASW | 0.0 | 1.8 | 98.2
| CHB | 0.0 | 0.0 | 0.0
| CHD | 0.0 | 1.9 | 98.1
| GIH | 0.0 | 6.1 | 93.9
| LWK | 0.0 | 1.8 | 98.2
| MEX | 0.0 | 0.0 | 0.0
| MKK | 0.0 | 3.9 | 96.1
| TSI | 0.0 | 5.2 | 94.8
| HapMapRevision=28
}}{{PharmGKB
|RSID=rs689469
|Name_s=PTGS2:10335G>A
|Gene_s=PTGS2
|Feature=
|Evidence=PubMed ID:15173859
|Annotation=Increased risk for colorectal cancer.
|Drugs=
|Drug Classes=
|Diseases=
|Curation Level=Curated
|PharmGKB Accession ID=PA161145108
}}

{{PMID|18085997}} Pyrosequencing of polymorphisms in the COX-2 gene (PTGS2) with reported clinical relevance.

{{GET Evidence
|impact=pharmacogenetic
|qualified_impact=Insufficiently evaluated pharmacogenetic
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs689469
|overall_frequency_n=1
|overall_frequency_d=126
|overall_frequency=0.00793651
|n_genomes=2
|n_genomes_annotated=0
|n_haplomes=2
|n_articles=1
|n_articles_annotated=0
|in_pharmgkb=Y
|autoscore=2
|webscore=N
|n_web_uneval=10
}}

{{PMID Auto
|PMID=23029430
|Title=Prognostic role of host cyclooxygenase and cytokine genotypes in a Caucasian cohort of patients with gastric adenocarcinoma.
|OA=1
}}

{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | Illumina Human 1M}}