{{Rsnum
|rsid=6897876
|Chromosome=5
|position=142308074
|Orientation=plus
|GMAF=0.4986
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(C;C)
|geno2=(C;T)
|geno3=(T;T)
}}{{ population diversity
| geno1=(C;C)
| geno2=(C;T)
| geno3=(T;T)
| CEU | 21.2 | 47.8 | 31.0
| HCB | 6.6 | 36.5 | 56.9
| JPT | 8.0 | 39.8 | 52.2
| YRI | 44.9 | 44.9 | 10.2
| ASW | 38.6 | 47.4 | 14.0
| CHB | 6.6 | 36.5 | 56.9
| CHD | 7.3 | 41.3 | 51.4
| GIH | 32.7 | 52.5 | 14.9
| LWK | 35.5 | 48.2 | 16.4
| MEX | 34.5 | 46.6 | 19.0
| MKK | 24.4 | 51.9 | 23.7
| TSI | 42.2 | 41.2 | 16.7
| HapMapRevision=28
}}Testicular germ cell tumor risk I("TGCT"; i.e. [[testicular cancer]] risk) was increased 40% per copy of the major allele (C) at [[rs4324715]] and [[rs6897876]] (OR = 1.37, CI: 1.14–1.64; OR = 1.39, CI: 1.16–1.66, respectively), based on a genome-wide scan of 277 primarily Caucasian TGCT cases and 919 controls. Men who have two copies of the common version of the sprouty 4 [[SPRY4]] gene have a 1.5-fold higher risk of testicular cancer than men who have two copies of the less common or minor version of the gene. [doi|10.1038/ng.393]

{{PMID Auto
|PMID=19483682
|Title=Common variation in KITLG and at 5q31.3 predisposes to testicular germ cell cancer.
|OA=1
}}

{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | Affy GenomeWide 6}}
{{on chip | FTDNA2}}
{{on chip | FTDNA}}
{{on chip | NatGeo2}}