{{Rsnum
|rsid=6902771
|Gene=ESR1
|Chromosome=6
|position=151836746
|Orientation=plus
|GMAF=0.4215
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(C;C)
|geno2=(C;T)
|geno3=(T;T)
|Gene_s=ESR1
}}{{ population diversity
| geno1=(C;C)
| geno2=(C;T)
| geno3=(T;T)
| CEU | 32.7 | 51.3 | 15.9
| HCB | 38.7 | 40.1 | 21.2
| JPT | 35.4 | 46.0 | 18.6
| YRI | 30.3 | 49.0 | 20.7
| ASW | 15.8 | 57.9 | 26.3
| CHB | 38.7 | 40.1 | 21.2
| CHD | 33.9 | 46.8 | 19.3
| GIH | 41.6 | 46.5 | 11.9
| LWK | 25.5 | 52.7 | 21.8
| MEX | 51.7 | 39.7 | 8.6
| MKK | 34.0 | 45.5 | 20.5
| TSI | 42.2 | 50.0 | 7.8
| HapMapRevision=28
}}{{PMID Auto GWAS
|PMID=19581569
|Trait=Alcohol dependence
|Title=Genome-wide association study of alcohol dependence
|RiskAllele=C
|Pval=0.000008
|OR=1.24
|ORtxt=[1.13-1.36]
}}

{{PMID Auto
|PMID=18053221
|Title=Impact of estrogen receptor gene polymorphisms and mRNA levels on obesity and lipolysis--a cohort study.
|OA=1
}}

{{PMID Auto
|PMID=18305958
|Title=Comprehensive evaluation of the estrogen receptor alpha gene reveals further evidence for association with type 2 diabetes enriched for nephropathy in an African American population.
|OA=1
}}

{{GET Evidence
|impact=pathogenic
|qualified_impact=Insufficiently evaluated pathogenic
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs6902771
|overall_frequency_n=53
|overall_frequency_d=128
|overall_frequency=0.414062
|n_genomes=36
|n_genomes_annotated=0
|n_haplomes=44
|n_articles=0
|n_articles_annotated=0
|in_gwas=Y
|autoscore=1
|webscore=N
}}

{{on chip | 23andMe v1}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | HumanOmni1Quad}}
{{on chip | Illumina Human 1M}}