{{Rsnum
|rsid=6917747
|Gene=IGF2R
|Chromosome=6
|position=159981673
|Orientation=plus
|GMAF=0.07668
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(A;A)
|geno2=(A;G)
|geno3=(G;G)
|Gene_s=IGF2R
}}{{ population diversity
| geno1=(A;A)
| geno2=(A;G)
| geno3=(G;G)
| CEU | 1.8 | 24.8 | 73.5
| HCB | 0.0 | 2.2 | 97.8
| JPT | 0.0 | 0.0 | 100.0
| YRI | 0.0 | 5.4 | 94.6
| ASW | 0.0 | 17.5 | 82.5
| CHB | 0.0 | 2.2 | 97.8
| CHD | 0.0 | 7.3 | 92.7
| GIH | 5.9 | 23.8 | 70.3
| LWK | 0.0 | 14.5 | 85.5
| MEX | 0.0 | 17.2 | 82.8
| MKK | 2.6 | 37.2 | 60.3
| TSI | 3.9 | 12.7 | 83.3
| HapMapRevision=28
}}{{PMID Auto GWAS
|PMID=19010793
|Trait=Brain lesion load
|Title=Genome-wide association analysis of susceptibility and clinical phenotype in multiple sclerosis
|RiskAllele=
|Pval=0.000007
|OR=NR
|ORtxt=NR
}}

{{PharmGKB
|RSID=rs6917747
|Name_s=
|Gene_s=IGF2R
|Feature=
|Evidence=PubMed ID:19010793; Web Resource:http://www.genome.gov/gwastudies/
|Annotation=GWAS results: Genome-wide association analysis of susceptibility and clinical phenotype in multiple sclerosis. (Initial Sample Size: 791 cases, 883 controls; Replication Sample Size: NR); (Region: 6q25.3; Reported Gene(s): IGF2R; Risk Allele: rs6917747-?); (p-value= 0.000007).This variant is associated with Brain lesion load.
|Drugs=
|Drug Classes=
|Diseases=
|Curation Level=Non-Curated
|PharmGKB Accession ID=PA164740337
}}

{{PMID|19307593|OA=1
}} Signals of recent positive selection in a worldwide sample of human populations.

{{GET Evidence
|impact=pathogenic
|qualified_impact=Insufficiently evaluated pathogenic
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs6917747
|overall_frequency_n=12
|overall_frequency_d=128
|overall_frequency=0.09375
|n_genomes=8
|n_genomes_annotated=0
|n_haplomes=8
|n_articles=0
|n_articles_annotated=0
|in_gwas=Y
|in_pharmgkb=Y
|autoscore=2
|webscore=N
}}

{{on chip | 23andMe v1}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | HumanOmni1Quad}}
{{on chip | Illumina Human 1M}}