{{Rsnum
|rsid=6919346
|Gene=LPA
|Chromosome=6
|position=160539327
|Orientation=plus
|GMAF=0.0854
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(C;C)
|geno2=(C;T)
|geno3=(T;T)
|Gene_s=LPA
}}{{ population diversity
| geno1=(C;C)
| geno2=(C;T)
| geno3=(T;T)
| CEU | 64.9 | 33.3 | 1.8
| HCB | 100.0 | 0.0 | 0.0
| JPT | 100.0 | 0.0 | 0.0
| YRI | 99.3 | 0.7 | 0.0
| ASW | 91.2 | 8.8 | 0.0
| CHB | 100.0 | 0.0 | 0.0
| CHD | 0.0 | 0.0 | 0.0
| GIH | 93.1 | 5.9 | 1.0
| LWK | 98.2 | 1.8 | 0.0
| MEX | 69.0 | 25.9 | 5.2
| MKK | 92.9 | 7.1 | 0.0
| TSI | 69.6 | 28.4 | 2.0
| HapMapRevision=28
}}{{PMID Auto GWAS
|PMID=19124843
|Trait=Plasma Lp (a) levels
|Title=Genome-wide association study of plasma Lp(a)levels Identifies multiple genes on chromosome 6q
|RiskAllele=
|Pval=4E-11
|OR=0.66
|ORtxt=[mg/dl decrease]
|OA=1
}}

{{PharmGKB
|RSID=rs6919346
|Name_s=
|Gene_s=-
|Feature=
|Evidence=PubMed ID:19124843; Web Resource:http://www.genome.gov/gwastudies/
|Annotation=GWAS results: Genome-wide association study of plasma Lp(a)levels Identifies multiple genes on chromosome 6q. (Initial Sample Size: 357 individuals; Replication Sample Size: 1,054 individuals); (Region: 6q25.3; Reported Gene(s): LPA; Risk Allele: rs6919346-?); (p-value= 0.00000000004).This variant is associated with Plasma Lp (a) levels.
|Drugs=
|Drug Classes=
|Diseases=
|Curation Level=Non-Curated
|PharmGKB Accession ID=PA164740076
}}

{{PMID Auto
|PMID=21127300
|Title=Genetic variation in LPAL2, LPA, and PLG predicts plasma lipoprotein(a) level and carotid artery disease risk.
|OA=1
}}

{{PMID Auto
|PMID=21283670
|Title=Single-nucleotide polymorphisms in LPA explain most of the ancestry-specific variation in Lp(a) levels in African Americans.
|OA=1
}}

{{PMID Auto
|PMID=21305047
|Title=Variation in LPA is associated with Lp(a) levels in three populations from the Third National Health and Nutrition Examination Survey.
|OA=1
}}

{{GET Evidence
|impact=pathogenic
|qualified_impact=Insufficiently evaluated pathogenic
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs6919346
|overall_frequency_n=110
|overall_frequency_d=128
|overall_frequency=0.859375
|n_genomes=54
|n_genomes_annotated=0
|n_haplomes=96
|n_articles=0
|n_articles_annotated=0
|in_gwas=Y
|in_pharmgkb=Y
|autoscore=2
|webscore=N
}}

{{on chip | 23andMe v1}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | Affy GenomeWide 6}}
{{on chip | Illumina Human 1M}}