{{Rsnum
|rsid=6957
|Gene=CCDC97
|Chromosome=19
|position=41324701
|Orientation=minus
|GMAF=0.2511
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(A;A)
|geno2=(A;G)
|geno3=(G;G)
|Gene_s=CCDC97
}}{{ population diversity
| geno1=(A;A)
| geno2=(A;G)
| geno3=(G;G)
| CEU | 72.6 | 26.5 | 0.9
| HCB | 43.1 | 41.6 | 15.3
| JPT | 54.9 | 33.6 | 11.5
| YRI | 51.7 | 42.2 | 6.1
| ASW | 59.6 | 31.6 | 8.8
| CHB | 43.1 | 41.6 | 15.3
| CHD | 50.5 | 42.2 | 7.3
| GIH | 60.4 | 34.7 | 5.0
| LWK | 46.4 | 41.8 | 11.8
| MEX | 58.6 | 37.9 | 3.4
| MKK | 48.1 | 42.3 | 9.6
| TSI | 64.7 | 32.4 | 2.9
| HapMapRevision=28
}}{{PMID|18281501}} [[colorectal neoplasia]]

271 colorectal adenoma cases and 544 controls, and 535 colorectal adenocarcinoma cases and 656 controls.
*[[rs6957]](A) was associated with higher serum TGFbeta-1 [means (in ng/mL) and 95% confidence interval (95% CI) for AA or AG, 32.6 (30.6-34.7); GG, 29.0 (25.1-32.9); P(difference) = 0.05] 
*[[rs11466345]](G;G) had a statistically significantly lower risk of adenocarcinoma [AG versus AA: odds ratio (OR), 0.9 (95% CI, 0.7-1.2); GG versus AA: OR, 0.4 (95% CI, 0.2-0.7); P(trend) = 0.01]. 
*The haplotype carrying both variants was also statistically significantly associated with a reduced risk of adenocarcinoma (OR, 0.3; 95% CI, 0.1-0.8)

{{PMID Auto
|PMID=19258388
|Title=Genetic variation in the transforming growth factor-{beta}1 gene is associated with susceptibility to IgA nephropathy.
|OA=1
}}

{{PMID Auto
|PMID=15175276
|Title=The transforming growth factor-beta1 (TGFB1) gene is associated with chronic obstructive pulmonary disease (COPD).
}}

{{PMID Auto
|PMID=16780585
|Title=Decorin and TGF-beta1 polymorphisms and development of COPD in a general population.
|OA=1
}}

{{PMID Auto
|PMID=18670143
|Title=The association of transforming growth factor beta 1 gene polymorphisms with the emphysema phenotype of COPD in Japanese.
}}

{{PMID Auto
|PMID=19096005
|Title=Variants in TGFB1, dust mite exposure, and disease severity in children with asthma.
|OA=1
}}

{{PMID Auto
|PMID=20479942
|Title=Genetic risk factors in lupus nephritis and IgA nephropathy--no support of an overlap.
|OA=1
}}

{{PMID Auto
|PMID=21320324
|Title=The role of IREB2 and transforming growth factor beta-1 genetic variants in COPD: a replication case-control study.
|OA=1
}}

{{PMID Auto
|PMID=21556788
|Title=Lack of association between the TGF-beta(1) gene and development of COPD in Asians: a case-control study and meta-analysis.
}}

{{PMID Auto
|PMID=23267696
|Title=Association of genetic polymorphisms with chronic obstructive pulmonary disease in the Chinese Han population: a case-control study
|OA=1
}}

{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | FTDNA2}}
{{on chip | HumanOmni1Quad}}
{{on chip | Illumina Human 1M}}