{{Rsnum
|rsid=6983561
|Chromosome=8
|position=127094635
|Orientation=plus
|GMAF=0.1864
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(A;A)
|geno2=(A;C)
|geno3=(C;C)
}}{{ population diversity
| geno1=(A;A)
| geno2=(A;C)
| geno3=(C;C)
| CEU | 95.4 | 4.6 | 0.0
| HCB | 48.9 | 44.4 | 6.7
| JPT | 70.5 | 29.5 | 0.0
| YRI | 19.0 | 44.4 | 36.5
| ASW | 0.0 | 0.0 | 0.0
| CHB | 48.9 | 44.4 | 6.7
| CHD | 0.0 | 0.0 | 0.0
| GIH | 0.0 | 0.0 | 0.0
| LWK | 0.0 | 0.0 | 0.0
| MEX | 0.0 | 0.0 | 0.0
| MKK | 0.0 | 0.0 | 0.0
| TSI | 0.0 | 0.0 | 0.0
| HapMapRevision=28
}}rs6983561 increases susceptibility to Prostate cancer 1.42 times for carriers of the C allele {{PMID|17401364|OA=1
}}

{{omim
|desc=PROSTATE CANCER, HEREDITARY, 10; HPC10
|id=611100
|rsnum=6983561
}}
{{PMID Auto
|PMID=19726753
|Title=Replication of prostate cancer risk loci in a Japanese case-control association study
}}
{{PMID Auto
|PMID=19843670
|Title=Association of Breast Cancer Susceptibility Variants with Risk of Pancreatic Cancer
|OA=1
}}
{{PMID Auto
|PMID=19908238
|Title=Common variants at 8q24 are associated with prostate cancer risk in Taiwanese men
}}

{{PMID Auto
|PMID=20717903
|Title=Evidence for an association between prostate cancer and chromosome 8q24 and 10q11 genetic variants in African American men: The flint men's health study
}}
{{PMID Auto
|PMID=21051319
|Title=Risk of Urinary Bladder Cancer is Associated with 8q24 Variant rs9642880[T]: Results from the Los Angeles-Shanghai Case-Control Study
|OA=1
}}

{{PMID Auto
|PMID=22234922
|Title=8q24 risk alleles in West African and Caribbean men
|OA=1
}}

{{PMID Auto
|PMID=22144497
|Title=Assessing the clinical role of genetic markers of early-onset prostate cancer among high-risk men enrolled in prostate cancer early detection
|OA=1
}}

{{PMID|17618282|OA=1
}} A common genetic risk factor for colorectal and prostate cancer.

{{PMID|17978284|OA=1
}} Confirmation study of prostate cancer risk variants at 8q24 in African Americans identifies a novel risk locus.

{{PMID|18231127|OA=1
}} 8q24 and prostate cancer: association with advanced disease and meta-analysis.

{{PMID|18360876|OA=1
}} Chromosome 8q24 markers: risk of early-onset and familial prostate cancer.

{{PMID|18483343}} Multiple independent genetic variants in the 8q24 region are associated with prostate cancer risk.

{{PMID|18535017|OA=1
}} Pooled analysis of genetic variation at chromosome 8q24 and colorectal neoplasia risk.

{{PMID|18577746|OA=1
}} Multiple loci with different cancer specificities within the 8q24 gene desert.

{{PMID|19058137|OA=1
}} Clinical utility of five genetic variants for predicting prostate cancer risk and mortality.

{{PMID|19366828|OA=1
}} Evaluation of 8q24 and 17q risk loci and prostate cancer mortality.

{{PMID|19520795|OA=1
}} Novel single nucleotide polymorphism associations with colorectal cancer on chromosome 8q24 in African and European Americans.

{{PMID|19549807|OA=1
}} Prostate cancer risk associated loci in African Americans.

{{PMID|19549893|OA=1
}} Evaluation of the 8q24 prostate cancer risk locus and MYC expression.

{{PMID|19602258|OA=1
}} Significance of common variants on human chromosome 8q24 in relation to the risk of prostate cancer in native Japanese men.

{{PMID|20026053}} WITHDRAWN: Relationships between 8q24 and 17q risk loci and sporadic or latent prostate cancer and the impacts of these loci on the clinicopathologic characteristics of prostate cancer.

{{PMID|20039378|OA=1
}} Estimation of genotype relative risks from pedigree data by retrospective likelihoods.

{{PMID|20584312|OA=1
}} 8q24 sequence variants in relation to prostate cancer risk among men of African descent: a case-control study.

{{PMID|20690139}} Meta-analysis of genome-wide and replication association studies on prostate cancer.

{{PMID|21557267}} A replication study examining three common single-nucleotide polymorphisms and the risk of prostate cancer in a Japanese population.

{{PMID|22382457|OA=1
}} Racial disparities in the association between variants on 8q24 and prostate cancer: a systematic review and meta-analysis.

{{PMID Auto GWAS
  |PMID=22923026
  |Trait=Prostate cancer
  |Title=Evaluating genetic risk for prostate cancer among Japanese and Latinos.
  |RiskAllele=C
  |Pval=4E-13
  |OR=1.87
  |ORtxt=[1.58-2.22]
  |OA=1
}}

{{PMID Auto
|PMID=24779299
|Title=Study of genetic variants of 8q21 and 8q24 associated with prostate cancer in Jing-Jin residents in northern China
}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | FTDNA2}}
{{on chip | FTDNA}}
{{on chip | HumanOmni1Quad}}