{{Rsnum
|rsid=7025486
|Gene=DAB2IP
|Chromosome=9
|position=121660124
|Orientation=plus
|GMAF=0.2603
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(A;A)
|geno2=(A;G)
|geno3=(G;G)
|Gene_s=DAB2IP
}}{{ population diversity
| geno1=(A;A)
| geno2=(A;G)
| geno3=(G;G)
| CEU | 8.0 | 33.6 | 58.4
| HCB | 10.2 | 38.0 | 51.8
| JPT | 5.3 | 29.2 | 65.5
| YRI | 17.0 | 46.9 | 36.1
| ASW | 8.8 | 42.1 | 49.1
| CHB | 10.2 | 38.0 | 51.8
| CHD | 6.4 | 45.9 | 47.7
| GIH | 9.0 | 48.0 | 43.0
| LWK | 7.3 | 36.4 | 56.4
| MEX | 3.4 | 34.5 | 62.1
| MKK | 3.2 | 37.2 | 59.6
| TSI | 1.0 | 34.3 | 64.7
| HapMapRevision=28
}}rs7025486(A) was associated with up to a 20% increased risk of the various vascular diseases, with an odds ratio of 1.21 for [[abdominal aortic aneurysm]] (AAA) (p = 4.6x10-10), 1.18 for early onset [[myocardial infarction]] (MI) (p = 3.1x10-5), 1.14 for [[peripheral arterial disease]] PAD (p = 3.9x10-5), and 1.2 for [[pulmonary embolism]] (PE) (p = 00030), but it was not associated with intracranial aneurysm or ischemic stroke. {{PMID|20622881}} An individual who carried two copies of this allele would have around a 44% increased risk of AAA. 

No association was seen between the A allele and common risk factors for arterial and venous disease—smoking, lipid levels, obesity, type 2 diabetes, and hypertension. [http://www.theheart.org/article/1097767.do theheart.org]

DeCode reports that the [[rs7025486(A;A)]] genotype is associated with 1.21x odds of [[peripheral arterial disease]] (PAD) {{PMID|18385739}} and 1.32x odds of [[abdominal aortic aneurysm]] (AAA) {{PMID|20622881}}. 

{{PMID Auto GWAS
|PMID=20622881
|Trait=Abdominal aortic aneurysm
|Title=Genome-wide association study identifies a sequence variant with the DAB2IP gene conferring susceptibility to abdominal aortic aneurysm
|RiskAllele=A
|Pval=5E-10
|OR=1.21
|ORtxt=[1.14-1.28]
}}

{{PMID Auto
|PMID=21444365
|Title=Association of a sequence variant in DAB2IP with coronary heart disease
|OA=1
}}

{{on chip | 23andMe v1}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | Affy GenomeWide 6}}
{{on chip | FTDNA2}}
{{on chip | FTDNA}}
{{on chip | HumanOmni1Quad}}
{{on chip | Illumina Human 1M}}