{{Rsnum
|rsid=7078160
|Gene=KIAA1598
|Chromosome=10
|position=118827560
|Orientation=plus
|GMAF=0.2658
|Gene_s=KIAA1598
|Assembly=GRCh37.p5
|GenomeBuild=37.3
|dbSNPBuild=137
|geno1=(A;A)
|geno2=(A;G)
|geno3=(G;G)
}}
{{ population diversity
| geno1=(A;A)
| geno2=(A;G)
| geno3=(G;G)
| CEU | 0.9 | 31.9 | 67.3
| HCB | 18.2 | 53.3 | 28.5
| JPT | 25.7 | 46.0 | 28.3
| YRI | 4.1 | 36.7 | 59.2
| ASW | 3.5 | 38.6 | 57.9
| CHB | 18.2 | 53.3 | 28.5
| CHD | 19.3 | 47.7 | 33.0
| GIH | 1.0 | 22.8 | 76.2
| LWK | 9.1 | 40.0 | 50.9
| MEX | 1.7 | 44.8 | 53.4
| MKK | 7.1 | 46.2 | 46.8
| TSI | 2.9 | 30.4 | 66.7
| HapMapRevision=28
}}{{PMID Auto GWAS
|PMID=20023658
|Trait=Nonsyndromic cleft lip with or without cleft palate
|Title=Genome-wide association study identifies two susceptibility loci for nonsyndromic cleft lip with or without cleft palate
|RiskAllele=A
|Pval=2E-8
|OR=1.36
|ORtxt=[1.21-1.53]
}}

{{PMID Auto
|PMID=20860768
|Title=Replication of two novel susceptibility loci for non-syndromic orofacial clefts in a Chinese population
}}

{{PMID Auto
|PMID=22021054
|Title=Polymorphic variants at 10q25.3 and 17q22 loci and the risk of non-syndromic cleft lip and palate in the Polish population.
}}

{{GET Evidence
|impact=pathogenic
|qualified_impact=Insufficiently evaluated pathogenic
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs7078160
|overall_frequency_n=34
|overall_frequency_d=128
|overall_frequency=0.265625
|n_genomes=24
|n_genomes_annotated=0
|n_haplomes=30
|n_articles=0
|n_articles_annotated=0
|in_gwas=Y
|autoscore=1
|webscore=N
}}

{{PMID Auto GWAS
  |PMID=22863734
  |Trait=Orofacial clefts
  |Title=Genome-wide meta-analyses of nonsyndromic cleft lip with or without cleft palate identify six new risk loci.
  |RiskAllele=A
  |Pval=6E-10
  |OR=NR
  |ORtxt=NR
  |OA=1
}}

{{PMID Auto
|PMID=23463464
|Title=Replication of genome wide association identified candidate genes confirm the role of common and rare variants in PAX7 and VAX1 in the etiology of nonsyndromic CL(P).
|OA=1
}}

{{on chip | 23andMe v1}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | HumanOmni1Quad}}
{{on chip | Illumina Human 1M}}