{{Rsnum
|rsid=710446
|Gene=KNG1
|Chromosome=3
|position=186742138
|Orientation=minus
|GMAF=0.4192
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(A;A)
|geno2=(A;G)
|geno3=(G;G)
|Gene_s=KNG1
}}{{ population diversity
| geno1=(A;A)
| geno2=(A;G)
| geno3=(G;G)
| CEU | 33.6 | 50.4 | 15.9
| HCB | 54.0 | 36.5 | 9.5
| JPT | 52.3 | 40.5 | 7.2
| YRI | 24.8 | 47.6 | 27.6
| ASW | 29.8 | 43.9 | 26.3
| CHB | 54.0 | 36.5 | 9.5
| CHD | 51.4 | 38.5 | 10.1
| GIH | 47.0 | 40.0 | 13.0
| LWK | 22.9 | 55.0 | 22.0
| MEX | 22.4 | 63.8 | 13.8
| MKK | 22.1 | 52.6 | 25.3
| TSI | 29.4 | 53.9 | 16.7
| HapMapRevision=28
}}{{PMID Auto GWAS
|PMID=20303064
|Trait=Activated partial thromboplastin time
|Title=Common Variants of Large Effect in F12, KNG1, and HRG Are Associated with Activated Partial Thromboplastin Time
|RiskAllele=G
|Pval=1E-21
|OR=0.36
|ORtxt=[0.29-0.43] unit decrease
|OA=1
}}

{{PMID Auto
|PMID=21270443
|Title=KNG1 Ile581Thr and susceptibility to venous thrombosis.
}}

{{PMID Auto GWAS
|PMID=22703881
|Trait=None
|Title=Genetic Associations for Activated Partial Thromboplastin Time and Prothrombin Time, their Gene Expression Profiles, and Risk of Coronary Artery Disease.
|RiskAllele=C
|Pval=0
|OR=1.1800
|ORtxt=None
|OA=1
}}

{{GET Evidence
|gene=KNG1
|aa_change=Ile581Thr
|aa_change_short=I581T
|impact=not reviewed
|qualified_impact=Insufficiently evaluated not reviewed
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs710446
|overall_frequency_n=60
|overall_frequency_d=128
|overall_frequency=0.46875
|n_genomes=38
|n_genomes_annotated=0
|n_haplomes=50
|n_articles=0
|n_articles_annotated=0
|nblosum100=3
|autoscore=0
|webscore=N
}}

{{PMID Auto
|PMID=22701019
|Title=A genome-wide association study identifies KNG1 as a genetic determinant of plasma factor XI Level and activated partial thromboplastin time.
}}

{{on chip | 23andMe v1}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | HumanOmni1Quad}}
{{on chip | Illumina Human 1M}}