{{Rsnum
|rsid=7115578
|Gene=MAML2
|Chromosome=11
|position=96266936
|Orientation=plus
|GMAF=0.4265
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(A;A)
|geno2=(A;G)
|geno3=(G;G)
|Gene_s=MAML2
}}{{ population diversity
| geno1=(A;A)
| geno2=(A;G)
| geno3=(G;G)
| CEU | 13.3 | 44.2 | 42.5
| HCB | 25.5 | 47.4 | 27.0
| JPT | 27.4 | 54.9 | 17.7
| YRI | 15.0 | 51.7 | 33.3
| ASW | 21.1 | 49.1 | 29.8
| CHB | 25.5 | 47.4 | 27.0
| CHD | 29.4 | 53.2 | 17.4
| GIH | 12.9 | 34.7 | 52.5
| LWK | 15.5 | 44.5 | 40.0
| MEX | 29.3 | 43.1 | 27.6
| MKK | 22.4 | 37.8 | 39.7
| TSI | 6.9 | 44.1 | 49.0
| HapMapRevision=28
}}{{PMID Auto GWAS
|PMID=19176441
|Trait=Treatment response for acute lymphoblastic leukemia
|Title=Genome-wide interrogation of germline genetic variation associated with treatment response in childhood acute lymphoblastic leukemia
|RiskAllele=A
|Pval=0.000008
|OR=1.86
|ORtxt=[1.23-2.79]
|OA=1
}}

{{PharmGKB
|RSID=rs7115578
|Name_s=
|Gene_s=MAML2
|Feature=
|Evidence=PubMed ID:19176441; Web Resource:http://www.genome.gov/gwastudies/
|Annotation=GWAS results: Genome-wide interrogation of germline genetic variation associated with treatment response in childhood acute lymphoblastic leukemia. (Initial Sample Size: 487 children; Replication Sample Size: NR); (Region: 11q21; Reported Gene(s): MAML2; Risk Allele: rs7115578-A); (p-value= 0.000008).This variant is associated with Treatment response for acute lymphoblastic leukemia.
|Drugs=
|Drug Classes=
|Diseases=Precursor Cell Lymphoblastic Leukemia-Lymphoma
|Curation Level=Non-Curated
|PharmGKB Accession ID=PA164740026
}}

{{PharmGKB
|RSID=rs7115578
|Name_s=
|Gene_s=MAML2
|Feature=
|Evidence=PubMed ID:19176441
|Annotation=This variant is associated with end-of-induction minimal risidual disease (MRD) in childhood acute lymphoblastic leukemia (ALL) from 2 independent cohorts (GWAS result). Risk Allele: A, MAF= 0.36, combined P value= 7.62E-06.
|Drugs=
|Drug Classes=
|Diseases=Neoplasm, Residual; Precursor Cell Lymphoblastic Leukemia-Lymphoma
|Curation Level=Curated
|PharmGKB Accession ID=PA162470161
}}

{{GET Evidence
|impact=pathogenic
|qualified_impact=Insufficiently evaluated pathogenic
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs7115578
|overall_frequency_n=56
|overall_frequency_d=128
|overall_frequency=0.4375
|n_genomes=37
|n_genomes_annotated=0
|n_haplomes=47
|n_articles=1
|n_articles_annotated=0
|in_gwas=Y
|in_pharmgkb=Y
|autoscore=2
|webscore=N
}}

{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | Affy GenomeWide 6}}
{{on chip | HumanOmni1Quad}}
{{on chip | Illumina Human 1M}}