{{Rsnum
|rsid=7138803
|Chromosome=12
|position=49853685
|Orientation=plus
|GMAF=0.292
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(A;A)
|geno2=(A;G)
|geno3=(G;G)
}}{{ population diversity
| geno1=(A;A)
| geno2=(A;G)
| geno3=(G;G)
| CEU | 12.4 | 44.2 | 43.4
| HCB | 8.0 | 41.6 | 50.4
| JPT | 8.0 | 53.1 | 38.9
| YRI | 2.7 | 27.2 | 70.1
| ASW | 5.3 | 29.8 | 64.9
| CHB | 8.0 | 41.6 | 50.4
| CHD | 6.4 | 33.0 | 60.6
| GIH | 21.8 | 34.7 | 43.6
| LWK | 5.5 | 25.5 | 69.1
| MEX | 7.0 | 33.3 | 59.6
| MKK | 0.6 | 23.7 | 75.6
| TSI | 11.8 | 52.0 | 36.3
| HapMapRevision=28
}}{{PMID Auto GWAS
|PMID=19079260
|Trait=Body mass index
|Title=Genome-wide association yields new sequence variants at seven loci that associate with measures of obesity
|RiskAllele=A
|Pval=1E-7
|OR=3.28
|ORtxt=[2.06-4.50] % SD
}}

{{PMID Auto GWAS
|PMID=19557197
|Trait=Waist circumference
|Title=NRXN3 Is a Novel Locus for Waist Circumference: A Genome-Wide Association Study from the CHARGE Consortium
|RiskAllele=
|Pval=8E-7
|OR=NR
|ORtxt=NR
|OA=1
}}

{{PharmGKB
|RSID=rs7138803
|Name_s=
|Gene_s=-
|Feature=
|Evidence=PubMed ID:19079260; Web Resource:http://www.genome.gov/gwastudies/
|Annotation=GWAS results: Genome-wide association yields new sequence variants at seven loci that associate with measures of obesity. (Initial Sample Size: 80,969 individuals; Replication Sample Size: 11,036 individuals); (Region: 12q13.13; Reported Gene(s): BCDIN3D, FAIM2; Risk Allele: rs7138803-A); (p-value= 0.0000002).This variant is associated with Weight.
|Drugs=
|Drug Classes=
|Diseases=
|Curation Level=Non-Curated
|PharmGKB Accession ID=PA164740173
}}

{{PharmGKB
|RSID=rs7138803
|Name_s=
|Gene_s=-
|Feature=
|Evidence=PubMed ID:19079260; Web Resource:http://www.genome.gov/gwastudies/
|Annotation=GWAS results: Genome-wide association yields new sequence variants at seven loci that associate with measures of obesity. (Initial Sample Size: 80,969 individuals; Replication Sample Size: 11,036 individuals); (Region: 12q13.13; Reported Gene(s): BCDIN3D, FAIM2; Risk Allele: rs7138803-A); (p-value= 0.0000001).This variant is associated with Body mass index.
|Drugs=
|Drug Classes=
|Diseases=
|Curation Level=Non-Curated
|PharmGKB Accession ID=PA164740155
}}
{{PMID Auto GWAS
|PMID=20935630
|Trait=None
|Title=Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index
|RiskAllele=A
|Pval=2E-17
|OR=0.12
|ORtxt=[0.08-0.16] kg/m2 increase
|OA=1
}}
{{PMID Auto
|PMID=20843981
|Title=Associations of six single nucleotide polymorphisms in obesity-related genes with BMI and risk of obesity in Chinese children
|OA=1
}}

{{PMID Auto
|PMID=21625854
|Title=Implication of genetic variants near TMEM18, BCDIN3D/FAIM2, and MC4R with coronary artery disease and obesity in Chinese: a angiography-based study
}}

{{PMID Auto
|PMID=21527513
|Title=Influence of physical inactivity on associations between single nucleotide polymorphisms and genetic predisposition to childhood obesity
}}

{{PMID Auto
|PMID=21912638
|Title=Studies of metabolic phenotypic correlates of 15 obesity associated gene variants
|OA=1
}}

{{PMID Auto
|PMID=22355368
|Title=Longitudinal Replication Studies of GWAS Risk SNPs Influencing Body Mass Index over the Course of Childhood and Adulthood
|OA=1
}}

{{PMID Auto
|PMID=19478790
|Title=The role of obesity-associated loci identified in genome-wide association studies in the determination of pediatric BMI.
|OA=1
}}

{{PMID Auto
|PMID=20127379
|Title=From monogenic to polygenic obesity: recent advances.
|OA=1
}}

{{PMID Auto
|PMID=20712903
|Title=Obesity and diabetes genes are associated with being born small for gestational age: results from the Auckland Birthweight Collaborative study.
|OA=1
}}

{{PMID Auto
|PMID=22041983
|Title=Recapitulation of genome-wide association studies on body mass index in the Korean population.
}}

{{GET Evidence
|impact=pathogenic
|qualified_impact=Insufficiently evaluated pathogenic
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs7138803
|overall_frequency_n=35
|overall_frequency_d=128
|overall_frequency=0.273438
|n_genomes=24
|n_genomes_annotated=0
|n_haplomes=31
|n_articles=0
|n_articles_annotated=0
|in_gwas=Y
|in_pharmgkb=Y
|autoscore=2
|webscore=N
}}

{{PMID Auto
|PMID=23924573
|Title=Common rs7138803 variant of FAIM2 and obesity in Han Chinese
|OA=1
}}

{{PMID Auto
|PMID=23424664
|Title=Study of 11 BMI-associated loci identified in GWAS for associations with central obesity in the Chinese children
|OA=1
}}

{{PMID Auto
|PMID=24269186
|Title=An obesity genetic risk score is associated with metabolic syndrome in Chinese children
}}

{{PMID Auto GWAS
  |PMID=23563607
  |Trait=Body mass index
  |Title=Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture.
  |RiskAllele=A
  |Pval=2E-9
  |OR=1.13
  |ORtxt=[NR]
  |OA=1
}}

{{PMID Auto
|PMID=24621099
|Title=Meta-analyses between 18 candidate genetic markers and overweight/obesity
|OA=1
}}

{{PMID Auto
|PMID=23471855
|Title=The genetics of childhood obesity and interaction with dietary macronutrients.
|OA=1
}}

{{PMID Auto
|PMID=23588626
|Title=Associations of obesity susceptibility loci with hypertension in Chinese children.
}}

{{on chip | 23andMe v1}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | Affy GenomeWide 6}}
{{on chip | HumanOmni1Quad}}
{{on chip | Illumina Human 1M}}