{{Rsnum
|rsid=7177192
|Gene=CASC5
|Chromosome=15
|position=40606445
|Orientation=plus
|ReferenceAllele=G
|MissenseAllele=C
|GMAF=0.3416
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(C;C)
|geno2=(C;G)
|geno3=(G;G)
|Gene_s=CASC5
}}{{ population diversity
| geno1=(C;C)
| geno2=(C;G)
| geno3=(G;G)
| CEU | 79.4 | 20.6 | 0.0
| HCB | 2.2 | 48.9 | 48.9
| JPT | 11.4 | 45.5 | 43.2
| YRI | 53.2 | 41.9 | 4.8
| ASW | 0.0 | 0.0 | 0.0
| CHB | 2.2 | 48.9 | 48.9
| CHD | 0.0 | 0.0 | 0.0
| GIH | 0.0 | 0.0 | 0.0
| LWK | 0.0 | 0.0 | 0.0
| MEX | 0.0 | 0.0 | 0.0
| MKK | 0.0 | 0.0 | 0.0
| TSI | 0.0 | 0.0 | 0.0
| HapMapRevision=28
}}{{Venter SNP
|rsid=7177192
|allele=C
|frequency=0.888
|uid=1103645593422
|type=homozygous_SNP
|hugo=CASC5
|ensembl gene=ENSG00000137812
|ensembl transcript=ENST00000346991
|sift=TOLERATED
|disease=A chromosomal aberration involving CASC5 is associated with acute myeloblastic leukemia (AML). Translocation t(11;15)(q23;q14) with MLL/HRX. May give rise to a MLL-CASC5 fusion protein.
}}

{{GET Evidence
|gene=CASC5
|aa_change=Arg43Thr
|aa_change_short=R43T
|impact=not reviewed
|qualified_impact=Insufficiently evaluated not reviewed
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs7177192
|overall_frequency_n=7787
|overall_frequency_d=9450
|overall_frequency=0.824021
|n_genomes=49
|n_genomes_annotated=0
|n_haplomes=70
|n_articles=0
|n_articles_annotated=0
|nblosum100=3
|autoscore=0
|webscore=N
}}

{{on chip | 23andMe v1}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | HumanOmni1Quad}}