{{Rsnum
|rsid=7250581
|Chromosome=19
|position=29573489
|Orientation=plus
|GMAF=0.07668
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(A;A)
|geno2=(A;G)
|geno3=(G;G)
}}{{ population diversity
| geno1=(A;A)
| geno2=(A;G)
| geno3=(G;G)
| CEU | 1.8 | 29.2 | 69.0
| HCB | 0.0 | 0.0 | 100.0
| JPT | 0.0 | 0.0 | 100.0
| YRI | 0.0 | 0.0 | 100.0
| ASW | 0.0 | 0.0 | 0.0
| CHB | 0.0 | 0.0 | 100.0
| CHD | 0.0 | 0.0 | 0.0
| GIH | 1.0 | 2.0 | 97.0
| LWK | 0.0 | 0.0 | 0.0
| MEX | 0.0 | 8.8 | 91.2
| MKK | 0.0 | 0.6 | 99.4
| TSI | 2.9 | 14.7 | 82.4
| HapMapRevision=28
}}
[[rs7250581]] has been reported in a large study to be associated with [[heart disease]], in particular, [[coronary artery disease]].

The risk allele (oriented to the dbSNP entry) is (G); the odds ratio associated with heterozygotes is 1.06 (CI 0.79-1.43), and for homozygotes, 1.40 (CI 1.05-1.86). {{PMID|17554300|OA=1
}}

{{PMID Auto
|PMID=19955471
|Title=Genetic Variants Identified in a European Genome-Wide Association Study That Were Found to Predict Incident Coronary Heart Disease in the Atherosclerosis Risk in Communities Study
|OA=1
}}

{{PMID Auto
|PMID=19956433
|Title=Genetics of coronary artery disease: focus on genome-wide association studies.
|OA=1
}}

{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | Affy GenomeWide 6}}
{{on chip | FTDNA2}}
{{on chip | FTDNA}}
{{on chip | HumanOmni1Quad}}