{{Rsnum
|rsid=7251
|Gene=IRF3
|Chromosome=19
|position=49659652
|Orientation=minus
|ReferenceAllele=G
|MissenseAllele=C
|GMAF=0.444
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(C;C)
|geno2=(C;G)
|geno3=(G;G)
|Gene_s=IRF3
}}{{ population diversity
| geno1=(C;C)
| geno2=(C;G)
| geno3=(G;G)
| CEU | 11.1 | 50.8 | 38.1
| HCB | 17.8 | 37.8 | 44.4
| JPT | 13.6 | 43.2 | 43.2
| YRI | 53.2 | 38.7 | 8.1
| ASW | 0.0 | 0.0 | 0.0
| CHB | 17.8 | 37.8 | 44.4
| CHD | 0.0 | 0.0 | 0.0
| GIH | 0.0 | 0.0 | 0.0
| LWK | 0.0 | 0.0 | 0.0
| MEX | 0.0 | 0.0 | 0.0
| MKK | 0.0 | 0.0 | 0.0
| TSI | 0.0 | 0.0 | 0.0
| HapMapRevision=28
}}{{PMID Auto
|PMID=19213861
|Title=No evidence for genetic association of interferon regulatory factor 3 in systemic lupus erythematosus
}}

{{PMID Auto
|PMID=19434718
|Title=Variants in interferon-alpha pathway genes and response to pegylated interferon-Alpha2a plus ribavirin for treatment of chronic hepatitis C virus infection in the hepatitis C antiviral long-term treatment against cirrhosis trial.
|OA=1
}}

{{GET Evidence
|gene=IRF3
|aa_change=Ser392Thr
|aa_change_short=S392T
|impact=not reviewed
|qualified_impact=Insufficiently evaluated not reviewed
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs7251
|n_genomes=1
|n_genomes_annotated=0
|n_haplomes=1
|n_articles=0
|n_articles_annotated=0
|nblosum100=-2
|autoscore=1
|webscore=N
}}

{{PMID Auto
|PMID=23542224
|Title=A variant in IRF3 impacts on the clinical outcome of AML patients submitted to Allo-SCT.
}}

{{on chip | 23andMe v1}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}