{{Rsnum
|rsid=72556554
|Chromosome=3
|Orientation=plus
|geno1=(A;A)
|geno2=(A;G)
|geno3=(G;G)
|Gene=TREX1
|position=48466996
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|Gene_s=TREX1
}}{{omim
|id=606609
|rsnum=72556554
|variant=0001
}}

{{ClinVar
|rsid=72556554
|Reversed=0
|FwdREF=G
|FwdALT=A
|REF=G
|ALT=A
|RSPOS=48508395
|CHROM=3
|dbSNPBuildID=130
|SSR=0
|SAO=1
|VP=0x050368000000040002110100
|GENEINFO=TREX1:11277
|GENE_NAME=TREX1
|GENE_ID=11277
|WGT=0
|VC=SNV
|CLNALLE=1
|CLNHGVS=NC_000003.11:g.48508395G>A
|CLNSRC=OMIM Allelic Variant
|CLNORIGIN=0
|CLNSRCID=606609.0001
|CLNSIG=255
|CLNCUI=C0796126
|CLNDBN=Aicardi Goutieres syndrome 1; Systemic lupus erythematosus, susceptibility to
|Disease=Aicardi Goutieres syndrome 1; Systemic lupus erythematosus
|CLNACC=RCV000004396.1; RCV000004397.1
|Tags=PM;PMC;S3D;SLO;VLD;OTHERKG;LSD;OM
|CLNDSDB=GeneReviews:MedGen:OMIM:Orphanet
|CLNDSDBID=NBK1475:C0796126:225750:51
}}

{{PMID|16845398}} Mutations in the gene encoding the 3'-5' DNA exonuclease TREX1 cause Aicardi-Goutieres syndrome at the AGS1 locus.

{{PMID|17660818}} Mutations in the gene encoding the 3'-5' DNA exonuclease TREX1 are associated with systemic lupus erythematosus.

{{PMID|17846997|OA=1
}} Clinical and molecular phenotype of Aicardi-Goutieres syndrome.

{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}