{{Rsnum
|rsid=72558189
|Gene=CYP2C9
|Chromosome=10
|position=94942234
|Orientation=plus
|ReferenceAllele=G
|MissenseAllele=A
|Summary=Warfarin (Coumadin®)
|geno1=(A;A)
|geno2=(A;G)
|geno3=(G;G)
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|Gene_s=CYP2C9
}}{{CPMC SNP
|link=https://cpmc.coriell.org/Sections/Results/Warfarin.aspx?PgId=222
}}[[rs72558189]], also known as 374G>A, 3552G>A or R125H, is a SNP in the [[CYP2C9]] gene.

The [[rs72558189]](A) allele defines the CYP2C9*14 variant, which may have decreased activity.{{ClinVar
|rsid=72558189
|Reversed=0
|FwdREF=G
|FwdALT=A
|REF=G
|ALT=A
|RSPOS=96701991
|CHROM=10
|dbSNPBuildID=130
|SSR=0
|SAO=1
|VP=0x050278000a01000002100100
|GENEINFO=CYP2C9:1559
|GENE_NAME=CYP2C9
|GENE_ID=1559
|WGT=1
|VC=SNV
|CLNALLE=1
|CLNHGVS=NC_000010.10:g.96701991G>A
|CLNORIGIN=0
|CLNSIG=1
|Tags=PM;TPA;PMC;S3D;NSM;REF;OTHERKG;LSD
}}{{PMID Auto
|PMID=15371982
|Title=Novel CYP2C9 genetic variants in Asian subjects and their influence on maintenance warfarin dose.
}}

{{PMID Auto
|PMID=16099926
|Title=Functional characterization of novel allelic variants of CYP2C9 recently discovered in southeast Asians.
}}