{{Rsnum
|rsid = 7283442
|Gene = LIPI
|Orientation=plus
|ReferenceAllele=A
|MissenseAllele=T
|geno1=(A;A)
|geno2=(A;T)
|geno3=(T;T)
|Chromosome=21
|position=14144655
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|Gene_s=LIPI
}}{{ population diversity
| geno1=(A;A)
| geno2=(A;T)
| geno3=(T;T)
| CEU | 100.0 | 0.0 | 0.0
| HCB | 100.0 | 0.0 | 0.0
| JPT | 100.0 | 0.0 | 0.0
| YRI | 100.0 | 0.0 | 0.0
| ASW | 0.0 | 0.0 | 0.0
| CHB | 100.0 | 0.0 | 0.0
| CHD | 0.0 | 0.0 | 0.0
| GIH | 0.0 | 0.0 | 0.0
| LWK | 0.0 | 0.0 | 0.0
| MEX | 0.0 | 0.0 | 0.0
| MKK | 0.0 | 0.0 | 0.0
| TSI | 0.0 | 0.0 | 0.0
| HapMapRevision=28
}}{{Venter SNP
|rsid=7283442
|allele=A
|frequency=
|uid=1103643073627
|type=homozygous_SNP
|hugo=LIPI
|ensembl gene=ENSG00000188992
|ensembl transcript=ENST00000344577
|sift=
|disease=Defects in LIPI may be a cause of susceptibility to familial hypertrigliceridemia (MIM:145750). Familial hypertriglyceridemia is a common inherited disorder in which the concentration of very low density lipoprotein (VLDL) is elevated in the plasma. This leads to increased risk of heart disease, obesity, and pancreatitis.
}}

{{ neighbor
| rsid = 2822432
| distance = 28
}}

{{GET Evidence
|gene=LIPI
|aa_change=Arg442Ser
|aa_change_short=R442S
|impact=not reviewed
|qualified_impact=Insufficiently evaluated not reviewed
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs7283442
|overall_frequency_n=122
|overall_frequency_d=122
|overall_frequency=1
|n_genomes=53
|n_genomes_annotated=0
|n_haplomes=106
|n_articles=0
|n_articles_annotated=0
|nblosum100=3
|autoscore=0
|webscore=N
}}

{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}