{{Rsnum
|rsid=7294
|Gene=VKORC1
|Chromosome=16
|position=31091000
|Orientation=minus
|GMAF=0.3108
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(A;A)
|geno2=(A;G)
|geno3=(G;G)
|Gene_s=VKORC1
}}{{ population diversity
| geno1=(A;A)
| geno2=(A;G)
| geno3=(G;G)
| CEU | 12.4 | 47.8 | 39.8
| HCB | 0.0 | 9.6 | 90.4
| JPT | 0.0 | 18.8 | 81.2
| YRI | 28.6 | 47.6 | 23.8
| ASW | 28.1 | 49.1 | 22.8
| CHB | 0.0 | 9.6 | 90.4
| CHD | 0.9 | 16.7 | 82.4
| GIH | 36.6 | 58.4 | 5.0
| LWK | 19.1 | 53.6 | 27.3
| MEX | 8.6 | 46.6 | 44.8
| MKK | 31.0 | 41.9 | 27.1
| TSI | 10.8 | 50.0 | 39.2
| HapMapRevision=28
}}
{{PMID Auto
|PMID=19436136
|Title=Association of sequence variations in vitamin K epoxide reductase and gamma-glutamyl carboxylase genes with biochemical measures of vitamin K status
|OA=1
}}

{{PharmGKB
|RSID=rs7294
|Name_s=VKORC1:G9041A; VKORC1:3730G>A
|Gene_s=VKORC1
|Feature=3' UTR
|Evidence=Web Resource:http://www.pharmgkb.org/search/annotatedGene/vkorc1/variant.jsp#ImportantVariantInformationforVKORC1-9041
|Annotation=May be associated with a higher warfarin dose phenotype
|Drugs=warfarin
|Drug Classes=
|Diseases=
|Curation Level=In-Depth
|PharmGKB Accession ID=PA161145141
}}

{{PMID Auto
|PMID=21127708
|Title=Genetic Variation of VKORC1 and CYP4F2 Genes Related to Warfarin Maintenance Dose in Patients with Myocardial Infarction
|OA=1
}}

{{PMID Auto
|PMID=21590310
|Title=Evaluation of the effects of VKORC1 polymorphisms and haplotypes, CYP2C9 genotypes, and clinical factors on warfarin response in Sudanese patients
}}

{{PMID Auto
|PMID=17048007
|Title=Association of warfarin dose with genes involved in its action and metabolism.
|OA=1
}}

{{PMID Auto
|PMID=18252229
|Title=Warfarin pharmacogenetics: CYP2C9 and VKORC1 genotypes predict different sensitivity and resistance frequencies in the Ashkenazi and Sephardi Jewish populations.
|OA=1
}}

{{PMID Auto
|PMID=18305455
|Title=Use of pharmacogenetic and clinical factors to predict the therapeutic dose of warfarin.
|OA=1
}}

{{PMID Auto
|PMID=18466099
|Title=Influence of CYP2C9 and VKORC1 on warfarin dose, anticoagulation attainment and maintenance among European-Americans and African-Americans.
|OA=1
}}

{{PMID Auto
|PMID=18523153
|Title=Regulatory polymorphism in vitamin K epoxide reductase complex subunit 1 (VKORC1) affects gene expression and warfarin dose requirement.
|OA=1
}}

{{PMID Auto
|PMID=18535201
|Title=A genome-wide scan for common genetic variants with a large influence on warfarin maintenance dose.
|OA=1
}}

{{PMID Auto
|PMID=18698231
|Title=Polymorphisms affecting gene transcription and mRNA processing in pharmacogenetic candidate genes: detection through allelic expression imbalance in human target tissues.
|OA=1
}}

{{PMID Auto
|PMID=18752379
|Title=Warfarin pharmacogenetics.
|OA=1
}}

{{PMID Auto
|PMID=18855533
|Title=VKORC1 polymorphisms, haplotypes and haplotype groups on warfarin dose among African-Americans and European-Americans.
|OA=1
}}

{{PMID Auto
|PMID=19226183
|Title=Donor-derived brain tumor following neural stem cell transplantation in an ataxia telangiectasia patient.
|OA=1
}}

{{PMID Auto
|PMID=19228618
|Title=Estimation of the warfarin dose with clinical and pharmacogenetic data.
|OA=1
}}

{{PMID Auto
|PMID=19955245
|Title=Warfarin sensitivity genotyping: a review of the literature and summary of patient experience.
|OA=1
}}

{{PMID Auto
|PMID=20018050
|Title=Application of sex-specific single-nucleotide polymorphism filters in genome-wide association data.
|OA=1
}}

{{PMID Auto
|PMID=21359226
|Title=The genomic ancestry of individuals from different geographical regions of Brazil is more uniform than expected.
|OA=1
}}

{{PMID Auto
|PMID=23208322
|Title=Influence of ORM1 polymorphisms on the maintenance stable warfarin dosage
}}

{{PMID Auto
|PMID=23662025
|Title=Genetic variation and haplotype structure of the gene Vitamin K epoxide reductase complex, subunit 1 in the Tamilian population
|OA=1
}}

{{PMID Auto
|PMID=23133420
|Title=Pharmacogenomic Diversity among Brazilians: Influence of Ancestry, Self-Reported Color, and Geographical Origin.
|OA=1
}}

{{on chip | 23andMe v1}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | Affy GenomeWide 6}}
{{on chip | FTDNA2}}
{{on chip | HumanOmni1Quad}}
{{on chip | Illumina Human 1M}}